methyl 3-({2,11,13,22-tetraoxa-1,12(1,3,2)-dibenzena-23(2,6)-pyridinabicyclo[10.10.1]tricosaphan-6,17-dien-1⁵-yl}methyloxy)benzoate

Base Information

• Chemical Name: methyl 3-({2,11,13,22-tetraoxa-1,12(1,3,2)-dibenzena-23(2,6)-pyridinabicyclo[10.10.1]tricosaphan-6,17-dien-1⁵-yl}methyloxy)benzoate
• CAS No.: 934990-51-9
• Molecular Formula: C₄₂H₄₅NO₇
• Molecular Weight: 675.822

Synonyms:methyl 3-({2,11,13,22-tetraoxa-1,12(1,3,2)-dibenzena-23(2,6)-pyridinabicyclo[10.10.1]tricosaphan-6,17-dien-1⁵-yl}methyloxy)benzoate

Chemical Property of methyl 3-({2,11,13,22-tetraoxa-1,12(1,3,2)-dibenzena-23(2,6)-pyridinabicyclo[10.10.1]tricosaphan-6,17-dien-1⁵-yl}methyloxy)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3-({2,11,13,22-tetraoxa-1,12(1,3,2)-dibenzena-23(2,6)-pyridinabicyclo[10.10.1]tricosaphan-6,17-dien-1⁵-yl}methyloxy)benzoate

There total 12 articles about methyl 3-({2,11,13,22-tetraoxa-1,12(1,3,2)-dibenzena-23(2,6)-pyridinabicyclo[10.10.1]tricosaphan-6,17-dien-1⁵-yl}methyloxy)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

15-(hydroxymethyl)-2,11,13,22-tetraoxa-1,12(1,3,2)-dibenzena-23(2,6)-pyridinabicyclo[10.10.1]tricosaphan-6,17-diene (934990-46-2) + methyl 3-hydroxybenzoate (19438-10-9) → methyl 3-({2,11,13,22-tetraoxa-1,12(1,3,2)-dibenzena-23(2,6)-pyridinabicyclo[10.10.1]tricosaphan-6,17-dien-15-yl}methyloxy)benzoate (934990-51-9)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 18h;

DOI:10.1002/ejoc.200600842

Reference yield:

2,6-Dibromopyridine (626-05-1) → methyl 3-({2,11,13,22-tetraoxa-1,12(1,3,2)-dibenzena-23(2,6)-pyridinabicyclo[10.10.1]tricosaphan-6,17-dien-15-yl}methyloxy)benzoate (934990-51-9)

Guidance literature:

Multi-step reaction with 5 steps

1: 81 percent / aq. Na₂CO₃ / Pd(PPh₃)4 / 1,2-dimethoxy-ethane / 18 h / Heating

2: 92 percent / aq. Na₂CO₃; Ba(OH)2*H₂O / Pd(PPh₃)4 / 1,2-dimethoxy-ethane; H₂O / 19 h / Heating

3: 92 percent / benzylidenebis(tricyclohexylphosphane)dichlororuthenium / CH₂Cl₂ / 48 h / 20 °C

4: 98 percent / Bu₄NF*3H₂O / tetrahydrofuran / 0.75 h / 20 °C

5: 87 percent / PPh₃; diisopropyl azodicarboxylate / tetrahydrofuran / 18 h / 20 °C

With barium dihydroxide; di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; sodium carbonate; triphenylphosphine; Grubbs catalyst first generation; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1,2-dimethoxyethane; dichloromethane; water; 1: Suzuki coupling / 2: Suzuki coupling / 5: Mitsunobu coupling;

DOI:10.1002/ejoc.200600842

Reference yield:

2-[2,6-bis(pent-4-enyloxy)phenyl]-6-[2,6-bis(pent-4-enyloxy)-4-(tert-butyldimethylsilyloxymethyl)phenyl]pyridine (934990-38-2) → methyl 3-({2,11,13,22-tetraoxa-1,12(1,3,2)-dibenzena-23(2,6)-pyridinabicyclo[10.10.1]tricosaphan-6,17-dien-15-yl}methyloxy)benzoate (934990-51-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 92 percent / benzylidenebis(tricyclohexylphosphane)dichlororuthenium / CH₂Cl₂ / 48 h / 20 °C

2: 98 percent / Bu₄NF*3H₂O / tetrahydrofuran / 0.75 h / 20 °C

3: 87 percent / PPh₃; diisopropyl azodicarboxylate / tetrahydrofuran / 18 h / 20 °C

With di-isopropyl azodicarboxylate; tetrabutyl ammonium fluoride; triphenylphosphine; Grubbs catalyst first generation; In tetrahydrofuran; dichloromethane; 3: Mitsunobu coupling;

DOI:10.1002/ejoc.200600842

upstream raw materials:

1⁵-(hydroxymethyl)-2,11,13,22-tetraoxa-1,12(1,3,2)-dibenzena-23(2,6)-pyridinabicyclo[10.10.1]tricosaphan-6,17-diene

methyl 3-hydroxybenzoate

2,6-Dibromopyridine

2-[2,6-bis(pent-4-enyloxy)phenyl]-6-bromopyridine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 934990-51-9 methyl 3-({2,11,13,22-tetraoxa-1,12(1,3,2)-dibenzena-23(2,6)-pyridinabicyclo[10.10.1]tricosaphan-6,17-dien-1⁵-yl}methyloxy)benzoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send