benzyl 4-[[{3-[(tert-butoxycarbonyl)amino]propylamino}thiocarbonyl]amino]butanoate

Base Information

• Chemical Name: benzyl 4-[[{3-[(tert-butoxycarbonyl)amino]propylamino}thiocarbonyl]amino]butanoate
• CAS No.: 936836-78-1
• Molecular Formula: C₂₀H₃₁N₃O₄S
• Molecular Weight: 409.55
• Mol file: 936836-78-1.mol

Synonyms:benzyl 4-[[{3-[(tert-butoxycarbonyl)amino]propylamino}thiocarbonyl]amino]butanoate

Chemical Property of benzyl 4-[[{3-[(tert-butoxycarbonyl)amino]propylamino}thiocarbonyl]amino]butanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl 4-[[{3-[(tert-butoxycarbonyl)amino]propylamino}thiocarbonyl]amino]butanoate

There total 1 articles about benzyl 4-[[{3-[(tert-butoxycarbonyl)amino]propylamino}thiocarbonyl]amino]butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

benzyl 4-((tert-butoxycarbonyl)amino)butanoate (95656-84-1) + (3-isothiocyanatopropyl)-carbamic acid tert-butyl ester (286955-45-1) → benzyl 4-[[{3-[(tert-butoxycarbonyl)amino]propylamino}thiocarbonyl]amino]butanoate (936836-78-1)

Guidance literature:

benzyl 4-((tert-butoxycarbonyl)amino)butanoate; With trifluoroacetic acid; In dichloromethane; for 1h;

(3-isothiocyanatopropyl)-carbamic acid tert-butyl ester; With triethylamine; In methanol; dichloromethane; for 18h; Further stages.;

DOI:10.1002/ejoc.200601004

Reference yield: 50.0%

benzyl 4-[[{3-[(tert-butoxycarbonyl)amino]propylamino}thiocarbonyl]amino]butanoate (936836-78-1) + 2,2,2-trifluoroacetamide (354-38-1) → benzyl 4-({3-[(tert-butoxycarbonyl)amino]propylamino}-[2,2,2-trifluoroacetylimino]methylamino)butanoate (936836-79-2)

Guidance literature:

benzyl 4-[[{3-[(tert-butoxycarbonyl)amino]propylamino}thiocarbonyl]amino]butanoate; With methyl iodide; In acetone; for 1h;

With ammonium hexafluorophosphate; In methanol; dichloromethane; for 18h;

2,2,2-trifluoroacetamide; With 1,8-diazabicyclo[5.4.0]undec-7-ene; In chloroform; toluene; for 1h; Further stages.; Heating;

DOI:10.1002/ejoc.200601004

upstream raw materials:

benzyl 4-((tert-butoxycarbonyl)amino)butanoate

(3-isothiocyanatopropyl)-carbamic acid tert-butyl ester

Downstream raw materials:

benzyl 4-({3-[(tert-butoxycarbonyl)amino]propylamino}-[2,2,2-trifluoroacetylimino]methylamino)butanoate