Benzyl-carbamic acid (2S,5R)-5-hydroxymethyl-2,5-dimethyl-tetrahydro-furan-2-ylmethyl ester

Base Information

• Chemical Name: Benzyl-carbamic acid (2S,5R)-5-hydroxymethyl-2,5-dimethyl-tetrahydro-furan-2-ylmethyl ester
• CAS No.: 126049-49-8
• Molecular Formula: C₁₆H₂₃NO₄
• Molecular Weight: 293.363
• Mol file: 126049-49-8.mol

Synonyms:Benzyl-carbamic acid (2S,5R)-5-hydroxymethyl-2,5-dimethyl-tetrahydro-furan-2-ylmethyl ester

Chemical Property of Benzyl-carbamic acid (2S,5R)-5-hydroxymethyl-2,5-dimethyl-tetrahydro-furan-2-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of Benzyl-carbamic acid (2S,5R)-5-hydroxymethyl-2,5-dimethyl-tetrahydro-furan-2-ylmethyl ester

There total 5 articles about Benzyl-carbamic acid (2S,5R)-5-hydroxymethyl-2,5-dimethyl-tetrahydro-furan-2-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

potassium cyanate (590-28-3) + 2,2-bis(hydroxymethyl)-tetrahydrofuran (13386-57-7) + 2-bromoheptane (1974-04-5) → (1-Methyl-hexyl)-carbamic acid 2-hydroxymethyl-tetrahydro-furan-2-ylmethyl ester (130399-51-8) + Benzyl-carbamic acid (2S,5R)-5-hydroxymethyl-2,5-dimethyl-tetrahydro-furan-2-ylmethyl ester (126049-49-8)

Guidance literature:

tetrabutylammomium bromide; In acetonitrile; at 100 ℃; for 24h;

DOI:10.1055/s-1990-26910

Reference yield: 87.0%

potassium cyanate (590-28-3) + ((2R,5S)-2,5-Di-tert-butyl-5-hydroxymethyl-tetrahydro-furan-2-yl)-methanol (130399-42-7) + 1-Bromooctadecane (112-89-0) → Benzyl-carbamic acid (2S,5R)-5-hydroxymethyl-2,5-dimethyl-tetrahydro-furan-2-ylmethyl ester (126049-49-8) + Octadecyl-carbamic acid (2R,5S)-2,5-di-tert-butyl-5-hydroxymethyl-tetrahydro-furan-2-ylmethyl ester (130399-48-3)

Guidance literature:

tetrabutylammomium bromide; In acetonitrile; at 100 ℃; for 24h;

DOI:10.1055/s-1990-26910

Reference yield: 87.0%

potassium cyanate (590-28-3) + ((2S,5R)-5-Hydroxymethyl-2,5-diphenyl-tetrahydro-furan-2-yl)-methanol (130399-41-6) + 1-Bromooctadecane (112-89-0) → Benzyl-carbamic acid (2S,5R)-5-hydroxymethyl-2,5-dimethyl-tetrahydro-furan-2-ylmethyl ester (126049-49-8) + Octadecyl-carbamic acid (2R,5S)-5-hydroxymethyl-2,5-diphenyl-tetrahydro-furan-2-ylmethyl ester (130399-47-2)

Guidance literature:

tetrabutylammomium bromide; In acetonitrile; at 100 ℃; for 24h;

DOI:10.1055/s-1990-26910

upstream raw materials:

potassium cyanate

2,2-bis(hydroxymethyl)-tetrahydrofuran

2-bromoheptane

cis-2,5-dimethyl-2,5-bis(hydroxymethyl)tetrahydrofuran