1-{(S)-2-[((S)-2-Methoxymethyl-pyrrolidin-1-ylmethyl)-dimethyl-silanyl]-2-phenyl-ethyl}-cyclohexanol

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Chemical Name:1-{(S)-2-[((S)-2-Methoxymethyl-pyrrolidin-1-ylmethyl)-dimethyl-silanyl]-2-phenyl-ethyl}-cyclohexanol
CAS No.:144712-73-2
Molecular Formula:C₂₃H₃₉NO₂Si
Molecular Weight:389.654
Hs Code.:

Synonyms:1-{(S)-2-[((S)-2-Methoxymethyl-pyrrolidin-1-ylmethyl)-dimethyl-silanyl]-2-phenyl-ethyl}-cyclohexanol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-{(S)-2-[((S)-2-Methoxymethyl-pyrrolidin-1-ylmethyl)-dimethyl-silanyl]-2-phenyl-ethyl}-cyclohexanol

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Technology Process of 1-{(S)-2-[((S)-2-Methoxymethyl-pyrrolidin-1-ylmethyl)-dimethyl-silanyl]-2-phenyl-ethyl}-cyclohexanol

There total 1 articles about 1-{(S)-2-[((S)-2-Methoxymethyl-pyrrolidin-1-ylmethyl)-dimethyl-silanyl]-2-phenyl-ethyl}-cyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 185-70-6
1-oxaspiro(2.5)octane

: 123463-20-7
[(S)-2-(methoxymethyl)pyrrolidinomethyl]dimethyl benzylsilane

: 144712-73-2
1-{(S)-2-[((S)-2-Methoxymethyl-pyrrolidin-1-ylmethyl)-dimethyl-silanyl]-2-phenyl-ethyl}-cyclohexanol

Guidance literature:: With sec.-butyllithium; Yield given. Multistep reaction; 1) cyclohexane, ether, -78 deg C, 1 h, 2) ether, cyclohexane, -50 deg C, 12 h;
DOI:10.1021/jo00049a012

Reference yield: 69.0%

: 144712-73-2
1-{(S)-2-[((S)-2-Methoxymethyl-pyrrolidin-1-ylmethyl)-dimethyl-silanyl]-2-phenyl-ethyl}-cyclohexanol

: 144712-74-3
1-((S)-2-Hydroxy-2-phenyl-ethyl)-cyclohexanol

Guidance literature:: With potassium fluoride; dihydrogen peroxide; potassium hydrogencarbonate; In tetrahydrofuran; methanol; Ambient temperature;
DOI:10.1021/jo00049a012