4-O-(t-butoxycarbonyl)-3-methyl-6-(2-oxopropyl)-2-(trimethylsilyl)ethoxy methylbenzoate

Base Information

Chemical Name:4-O-(t-butoxycarbonyl)-3-methyl-6-(2-oxopropyl)-2-(trimethylsilyl)ethoxy methylbenzoate
CAS No.:908291-87-2
Molecular Formula:C₂₂H₃₄O₇Si
Molecular Weight:438.593
Hs Code.:

Synonyms:4-O-(t-butoxycarbonyl)-3-methyl-6-(2-oxopropyl)-2-(trimethylsilyl)ethoxy methylbenzoate

Suppliers and Price of 4-O-(t-butoxycarbonyl)-3-methyl-6-(2-oxopropyl)-2-(trimethylsilyl)ethoxy methylbenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-O-(t-butoxycarbonyl)-3-methyl-6-(2-oxopropyl)-2-(trimethylsilyl)ethoxy methylbenzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-O-(t-butoxycarbonyl)-3-methyl-6-(2-oxopropyl)-2-(trimethylsilyl)ethoxy methylbenzoate

There total 5 articles about 4-O-(t-butoxycarbonyl)-3-methyl-6-(2-oxopropyl)-2-(trimethylsilyl)ethoxy methylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 908291-86-1
4-O-(t-butoxycarbonyl)-3,6-dimethyl-2-(trimethylsilyl)ethoxy methylbenzoate

: 78191-00-1
N-Methoxy-N-methylacetamide

: 908291-87-2
4-O-(t-butoxycarbonyl)-3-methyl-6-(2-oxopropyl)-2-(trimethylsilyl)ethoxy methylbenzoate

Guidance literature:: 4-O-(t-butoxycarbonyl)-3,6-dimethyl-2-(trimethylsilyl)ethoxy methylbenzoate; With n-butyllithium; diisopropylamine; In tetrahydrofuran; at -78 - 0 ℃;

N-Methoxy-N-methylacetamide; With N,N,N,N,-tetramethylethylenediamine; at -78 ℃; for 2h;
DOI:10.1021/ol0610993

Reference yield:

: 908292-00-2
4-O-(t-butoxycarbonyl)-2-hydroxy-3,6-dimethyl methylbenzoate

: 908291-87-2
4-O-(t-butoxycarbonyl)-3-methyl-6-(2-oxopropyl)-2-(trimethylsilyl)ethoxy methylbenzoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 99 percent / triphenylphosphine; diisopropyl diazodicarboxylate / tetrahydrofuran / 1 h

2.1: diisopropylamine; nBuLi / tetrahydrofuran; various solvent(s) / -78 - 0 °C

2.2: 81 percent / N,N,N',N'-tetramethylethylenediamine / 2 h / -78 °C

With n-butyllithium; di-isopropyl azodicarboxylate; diisopropylamine; triphenylphosphine; In tetrahydrofuran; 1.1: Mitsunobu reaction;
DOI:10.1021/ol0610993

Reference yield:

: 2916-68-9
2-(Trimethylsilyl)ethanol

: 908291-87-2
4-O-(t-butoxycarbonyl)-3-methyl-6-(2-oxopropyl)-2-(trimethylsilyl)ethoxy methylbenzoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 99 percent / triphenylphosphine; diisopropyl diazodicarboxylate / tetrahydrofuran / 1 h

2.1: diisopropylamine; nBuLi / tetrahydrofuran; various solvent(s) / -78 - 0 °C

2.2: 81 percent / N,N,N',N'-tetramethylethylenediamine / 2 h / -78 °C

With n-butyllithium; di-isopropyl azodicarboxylate; diisopropylamine; triphenylphosphine; In tetrahydrofuran; 1.1: Mitsunobu reaction;
DOI:10.1021/ol0610993