1-(tert-butyl-dimethyl-silanyloxy)-6-[3-(tert-butyl-diphenyl-silanyloxy)-1-methyl-propyl]-2,2-dimethyl-oct-7-en-4-ol

Base Information

Chemical Name:1-(tert-butyl-dimethyl-silanyloxy)-6-[3-(tert-butyl-diphenyl-silanyloxy)-1-methyl-propyl]-2,2-dimethyl-oct-7-en-4-ol
CAS No.:281661-44-7
Molecular Formula:C₃₆H₆₀O₃Si₂
Molecular Weight:597.042
Hs Code.:

1-(<i>tert</i>-butyl-dimethyl-silanyloxy)-6-[3-(<i>tert</i>-butyl-diphenyl-silanyloxy)-1-methyl-propyl]-2,2-dimethyl-oct-7-en-4-ol

Synonyms:1-(tert-butyl-dimethyl-silanyloxy)-6-[3-(tert-butyl-diphenyl-silanyloxy)-1-methyl-propyl]-2,2-dimethyl-oct-7-en-4-ol

Suppliers and Price of 1-(tert-butyl-dimethyl-silanyloxy)-6-[3-(tert-butyl-diphenyl-silanyloxy)-1-methyl-propyl]-2,2-dimethyl-oct-7-en-4-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(tert-butyl-dimethyl-silanyloxy)-6-[3-(tert-butyl-diphenyl-silanyloxy)-1-methyl-propyl]-2,2-dimethyl-oct-7-en-4-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(tert-butyl-dimethyl-silanyloxy)-6-[3-(tert-butyl-diphenyl-silanyloxy)-1-methyl-propyl]-2,2-dimethyl-oct-7-en-4-ol

There total 7 articles about 1-(tert-butyl-dimethyl-silanyloxy)-6-[3-(tert-butyl-diphenyl-silanyloxy)-1-methyl-propyl]-2,2-dimethyl-oct-7-en-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 281661-52-7
3-[3-(tert-butyl-diphenyl-silanyloxy)-1-methyl-propyl]-pent-4-en-1-ol

: 281661-44-7
1-(tert-butyl-dimethyl-silanyloxy)-6-[3-(tert-butyl-diphenyl-silanyloxy)-1-methyl-propyl]-2,2-dimethyl-oct-7-en-4-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: 89 percent / oxalyl chloride; Et₃N; DMSO / CH₂Cl₂ / 0.25 h / -60 - -50 °C

2.1: Mg / 0 °C

2.2: 83 percent / tetrahydrofuran / 1 h / 20 °C

With oxalyl dichloride; magnesium; dimethyl sulfoxide; triethylamine; In dichloromethane; 1.1: Swern oxidation / 2.1: Solid phase reaction / 2.2: Grignard reaction;
DOI:10.1021/jo9918450

Reference yield:

: 281661-38-9
3-[3-(tert-butyl-diphenyl-silanyloxy)-1-methyl-propyl]-pent-4-enoic acid methyl ester

: 281661-44-7
1-(tert-butyl-dimethyl-silanyloxy)-6-[3-(tert-butyl-diphenyl-silanyloxy)-1-methyl-propyl]-2,2-dimethyl-oct-7-en-4-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: 99 percent / LiAlH₄ / diethyl ether / 1.5 h / 0 °C

2.1: 89 percent / oxalyl chloride; Et₃N; DMSO / CH₂Cl₂ / 0.25 h / -60 - -50 °C

3.1: Mg / 0 °C

3.2: 83 percent / tetrahydrofuran / 1 h / 20 °C

With lithium aluminium tetrahydride; oxalyl dichloride; magnesium; dimethyl sulfoxide; triethylamine; In diethyl ether; dichloromethane; 1.1: Reduction / 2.1: Swern oxidation / 3.1: Solid phase reaction / 3.2: Grignard reaction;
DOI:10.1021/jo9918450

Reference yield:

: 281661-33-4
(E)-(R)-6-(tert-Butyl-diphenyl-silanyloxy)-4-methyl-hex-2-enal

: 281661-44-7
1-(tert-butyl-dimethyl-silanyloxy)-6-[3-(tert-butyl-diphenyl-silanyloxy)-1-methyl-propyl]-2,2-dimethyl-oct-7-en-4-ol

Guidance literature:: Multi-step reaction with 5 steps

1.1: H₂O₂; NaH₂PO₄; NaClO₂ / acetonitrile; H₂O / 21 h / 20 °C

1.2: 79 percent / diethyl ether

2.1: 34 percent / tetrahydrofuran / 1.5 h / -40 °C

3.1: 99 percent / LiAlH₄ / diethyl ether / 1.5 h / 0 °C

4.1: 89 percent / oxalyl chloride; Et₃N; DMSO / CH₂Cl₂ / 0.25 h / -60 - -50 °C

5.1: Mg / 0 °C

5.2: 83 percent / tetrahydrofuran / 1 h / 20 °C

With sodium chlorite; sodium dihydrogenphosphate; lithium aluminium tetrahydride; oxalyl dichloride; dihydrogen peroxide; magnesium; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; diethyl ether; dichloromethane; water; acetonitrile; 1.1: Carboxylation / 1.2: Alkylation / 2.1: Grignard reaction / 3.1: Reduction / 4.1: Swern oxidation / 5.1: Solid phase reaction / 5.2: Grignard reaction;
DOI:10.1021/jo9918450