dimethylisobutyryl phosphate p-methylbenzenesulfonylhydrazone

Base Information

• Chemical Name: dimethylisobutyryl phosphate p-methylbenzenesulfonylhydrazone
• CAS No.: 26584-02-1
• Molecular Formula: C₁₃H₂₁N₂O₅PS
• Molecular Weight: 348.36
• Mol file: 26584-02-1.mol

Synonyms:dimethylisobutyryl phosphate p-methylbenzenesulfonylhydrazone

Chemical Property of dimethylisobutyryl phosphate p-methylbenzenesulfonylhydrazone

Chemical Property:

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Technology Process of dimethylisobutyryl phosphate p-methylbenzenesulfonylhydrazone

There total 1 articles about dimethylisobutyryl phosphate p-methylbenzenesulfonylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

Dimethyl (2-methyl-1-oxopropyl)phosphonate (6918-58-7) + toluene-4-sulfonic acid hydrazide (1576-35-8) → dimethylisobutyryl phosphate p-methylbenzenesulfonylhydrazone (26584-02-1)

Guidance literature:

toluene-4-sulfonic acid hydrazide; With hydrogenchloride; In tetrahydrofuran; water; at 0 ℃; for 0.333333h;

Dimethyl (2-methyl-1-oxopropyl)phosphonate; In tetrahydrofuran; water; at 0 - 20 ℃; for 6h;

DOI:10.1021/acs.joc.5b00629

Reference yield: 58.0%

dimethylisobutyryl phosphate p-methylbenzenesulfonylhydrazone (26584-02-1) + phenylacetylene (536-74-3) → dimethyl (4-methyl-1-phenylpenta-1,2-dien-3-yl)phosphonate

Guidance literature:

With copper(l) iodide; diisopropylamine; In 1,4-dioxane; at 80 ℃; for 3h; Inert atmosphere; Schlenk technique;

DOI:10.1055/s-0035-1561298

Reference yield: 50.0%

bromobenzene (108-86-1,52753-63-6) + dimethylisobutyryl phosphate p-methylbenzenesulfonylhydrazone (26584-02-1) → dimethyl (2-methyl-1-phenylprop-1-en-1-yl)phosphonate

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In 1,4-dioxane; at 90 ℃; for 3h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.joc.5b00629

upstream raw materials:

Dimethyl (2-methyl-1-oxopropyl)phosphonate

toluene-4-sulfonic acid hydrazide