5'-deoxy-5'-(4-methoxytrityl)amino-2'-triisopropylsilyloxymethyluridine

Base Information

Chemical Name:5'-deoxy-5'-(4-methoxytrityl)amino-2'-triisopropylsilyloxymethyluridine
CAS No.:1558008-07-3
Molecular Formula:C₃₉H₅₁N₃O₇Si
Molecular Weight:701.935
Hs Code.:

Synonyms:5'-deoxy-5'-(4-methoxytrityl)amino-2'-triisopropylsilyloxymethyluridine

Suppliers and Price of 5'-deoxy-5'-(4-methoxytrityl)amino-2'-triisopropylsilyloxymethyluridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5'-deoxy-5'-(4-methoxytrityl)amino-2'-triisopropylsilyloxymethyluridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5'-deoxy-5'-(4-methoxytrityl)amino-2'-triisopropylsilyloxymethyluridine

There total 4 articles about 5'-deoxy-5'-(4-methoxytrityl)amino-2'-triisopropylsilyloxymethyluridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 1558008-06-2
5'-amino-5'-deoxy-2'-O-triisopropylsilyloxymethyluridine

: 14470-28-1
mono-4-methoxytrityl chloride

: 1558008-07-3
5'-deoxy-5'-(4-methoxytrityl)amino-2'-triisopropylsilyloxymethyluridine

Guidance literature:: With pyridine; at 0 - 20 ℃;
DOI:10.1039/c3ob42532k

Reference yield:

: 217300-17-9
chloromethoxy-triisopropyl-silane

: 1558008-07-3
5'-deoxy-5'-(4-methoxytrityl)amino-2'-triisopropylsilyloxymethyluridine

Guidance literature:: Multi-step reaction with 3 steps

1.1: dibutyltin chloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / 20 °C / Inert atmosphere

1.2: 0.5 h / 80 °C / Inert atmosphere

2.1: hydrogen sulfide; pyridine / water / 20 °C

3.1: pyridine / 0 - 20 °C

With pyridine; hydrogen sulfide; dibutyltin chloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; water;
DOI:10.1039/c3ob42532k

Reference yield:

: 39483-48-2
5'-azido-5'-deoxyuridine

: 1558008-07-3
5'-deoxy-5'-(4-methoxytrityl)amino-2'-triisopropylsilyloxymethyluridine

Guidance literature:: Multi-step reaction with 3 steps

1.1: dibutyltin chloride; N-ethyl-N,N-diisopropylamine / dichloromethane / 1 h / 20 °C / Inert atmosphere

1.2: 0.5 h / 80 °C / Inert atmosphere

2.1: hydrogen sulfide; pyridine / water / 20 °C

3.1: pyridine / 0 - 20 °C

With pyridine; hydrogen sulfide; dibutyltin chloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; water;
DOI:10.1039/c3ob42532k