2-(2-chlorophenyl)-3-(1-(4-chlorophenyl)-1H-tetrazol-5-yl)imidazo[1,2-a]pyridine

Base Information

Chemical Name:2-(2-chlorophenyl)-3-(1-(4-chlorophenyl)-1H-tetrazol-5-yl)imidazo[1,2-a]pyridine
CAS No.:1426521-56-3
Molecular Formula:C₂₀H₁₂Cl₂N₆
Molecular Weight:407.261
Hs Code.:

Synonyms:2-(2-chlorophenyl)-3-(1-(4-chlorophenyl)-1H-tetrazol-5-yl)imidazo[1,2-a]pyridine

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Chemical Property of 2-(2-chlorophenyl)-3-(1-(4-chlorophenyl)-1H-tetrazol-5-yl)imidazo[1,2-a]pyridine

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Technology Process of 2-(2-chlorophenyl)-3-(1-(4-chlorophenyl)-1H-tetrazol-5-yl)imidazo[1,2-a]pyridine

There total 8 articles about 2-(2-chlorophenyl)-3-(1-(4-chlorophenyl)-1H-tetrazol-5-yl)imidazo[1,2-a]pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1426521-38-1
2-(2-chlorophenyl)-N-(4-chlorophenyl)imidazo[1,2-a]pyridine-3-carbohydrazonamide

: 1426521-56-3
2-(2-chlorophenyl)-3-(1-(4-chlorophenyl)-1H-tetrazol-5-yl)imidazo[1,2-a]pyridine

Guidance literature:: With acetic acid; sodium nitrite; In water; at 0 - 20 ℃; for 1h;

Reference yield:

: 1426521-40-5
2-(2-chlorophenyl)-N-(4-chlorophenyl)imidazo[1,2-a]pyridine-3-carbothioamide

: 1426521-56-3
2-(2-chlorophenyl)-3-(1-(4-chlorophenyl)-1H-tetrazol-5-yl)imidazo[1,2-a]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / ethanol / 1 h / 70 °C

2: acetic acid; sodium nitrite / water / 1 h / 0 - 20 °C

With hydrazine hydrate; acetic acid; sodium nitrite; In ethanol; water;

Reference yield:

: 1426521-20-1
ethyl 2-(2-chlorophenyl)imidazo[1,2-a]pyridine-3-carboxylate

: 1426521-56-3
2-(2-chlorophenyl)-3-(1-(4-chlorophenyl)-1H-tetrazol-5-yl)imidazo[1,2-a]pyridine

Guidance literature:: Multi-step reaction with 6 steps

1.1: lithium hydroxide / methanol; water / 2 h / 70 °C

1.2: pH 4

2.1: thionyl chloride / 2 h / 100 °C

3.1: triethylamine / dichloromethane / 3 h / 20 °C

4.1: Lawessons reagent / toluene / 4 h / 150 °C / Microwave irradiation

5.1: hydrazine hydrate / ethanol / 1 h / 70 °C

6.1: acetic acid; sodium nitrite / water / 1 h / 0 - 20 °C

With Lawessons reagent; thionyl chloride; hydrazine hydrate; acetic acid; triethylamine; lithium hydroxide; sodium nitrite; In methanol; ethanol; dichloromethane; water; toluene;