(1,4-Bis(3,4,5-trimethoxybenzoyl)-2-piperazinyl)methyl butanoate

Base Information

Chemical Name:(1,4-Bis(3,4,5-trimethoxybenzoyl)-2-piperazinyl)methyl butanoate
CAS No.:129243-05-6
Molecular Formula:C₂₉H₃₈N₂O₁₀
Molecular Weight:574.628
Hs Code.:
DSSTox Substance ID:DTXSID40926356
ChEMBL ID:CHEMBL6341

Synonyms:(1,4-Bis(3,4,5-trimethoxybenzoyl)-2-piperazinyl)methyl butanoate;CHEMBL6341;129243-05-6;N,N'-Di-(3',4',5'-trimethoxybenzoyl)-2-n-butanoyloxymethylpiperazine;Butanoic acid, (1,4-bis(3,4,5-trimethoxybenzoyl)-2-piperazinyl)methyl ester;SCHEMBL10470709;DTXSID40926356;C29H38N2O10;[1,4-bis(3,4,5-trimethoxybenzoyl)piperazin-2-yl]methyl butanoate;BDBM50046964;C29-H38-N2-O10;LS-46123;Butyric acid 1,4-bis-(3,4,5-trimethoxy-benzoyl)-piperazin-2-ylmethyl ester

Suppliers and Price of (1,4-Bis(3,4,5-trimethoxybenzoyl)-2-piperazinyl)methyl butanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (1,4-Bis(3,4,5-trimethoxybenzoyl)-2-piperazinyl)methyl butanoate

Chemical Property:

Vapor Pressure:2.69E-21mmHg at 25°C
Boiling Point:732.2°C at 760 mmHg
Flash Point:396.6°C
Density:1.204g/cm³
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:10
Rotatable Bond Count:13
Exact Mass:574.25264541
Heavy Atom Count:41
Complexity:832

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCCC(=O)OCC1CN(CCN1C(=O)C2=CC(=C(C(=C2)OC)OC)OC)C(=O)C3=CC(=C(C(=C3)OC)OC)OC

Technology Process of (1,4-Bis(3,4,5-trimethoxybenzoyl)-2-piperazinyl)methyl butanoate

There total 3 articles about (1,4-Bis(3,4,5-trimethoxybenzoyl)-2-piperazinyl)methyl butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 4521-61-3
3,4,5-Trimethoxybenzoyl chloride

: Butyric acid piperazin-2-ylmethyl ester; hydrochloride

: 129243-05-6
Butyric acid 1,4-bis-(3,4,5-trimethoxy-benzoyl)-piperazin-2-ylmethyl ester

Guidance literature:: With triethylamine; In benzene; Ambient temperature;
DOI:10.1021/jm00060a006

Reference yield:

: 148227-83-2
Butyric acid 1,4-dibenzyl-piperazin-2-ylmethyl ester

: 129243-05-6
Butyric acid 1,4-bis-(3,4,5-trimethoxy-benzoyl)-piperazin-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: H₂, conc. HCl / 10percent Pd/C / ethanol / 40 °C / 2068.6 Torr

2: 72 percent / Et₃N / benzene / Ambient temperature

With hydrogenchloride; hydrogen; triethylamine; palladium on activated charcoal; In ethanol; benzene;
DOI:10.1021/jm00060a006

Reference yield:

: 94437-04-4,148228-25-5,148228-26-6
1,4-dibenzyl-2-hydroxypiperazine

: 129243-05-6
Butyric acid 1,4-bis-(3,4,5-trimethoxy-benzoyl)-piperazin-2-ylmethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / Et₃N / benzene / Ambient temperature

2: H₂, conc. HCl / 10percent Pd/C / ethanol / 40 °C / 2068.6 Torr

3: 72 percent / Et₃N / benzene / Ambient temperature

With hydrogenchloride; hydrogen; triethylamine; palladium on activated charcoal; In ethanol; benzene;
DOI:10.1021/jm00060a006