(E)-2-ethyl-5-styrylthiophene

Base Information

• Chemical Name: (E)-2-ethyl-5-styrylthiophene
• CAS No.: 36634-74-9
• Molecular Formula: C₁₄H₁₄S
• Molecular Weight: 214.331
• Mol file: 36634-74-9.mol

Synonyms:(E)-2-ethyl-5-styrylthiophene

Chemical Property of (E)-2-ethyl-5-styrylthiophene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-2-ethyl-5-styrylthiophene

There total 4 articles about (E)-2-ethyl-5-styrylthiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2-ethylthiophene (872-55-9) + styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) → (E)-2-ethyl-5-styrylthiophene (36634-74-9)

Guidance literature:

With palladium diacetate; p-benzoquinone; In acetic acid; dimethyl sulfoxide; at 20 ℃; for 24h;

DOI:10.1002/chem.201101992

Reference yield:

→ (E)-2-ethyl-5-styrylthiophene (36634-74-9)

Guidance literature:

With potassium hydroxide; hydrazine hydrate; diethylene glycol; at 200 ℃;

Reference yield:

5-ethyl-thiophene-2-carbaldehyde (36880-33-8) + benzylmagnesium chloride (6921-34-2) → (E)-2-ethyl-5-styrylthiophene (36634-74-9)

Guidance literature:

With diethyl ether; Erhitzen des nach der Hydrolyse erhaltenen Reaktionsprodukts mit Ameisensaeure;

upstream raw materials:

5-ethyl-thiophene-2-carbaldehyde

benzylmagnesium chloride

2-ethylthiophene

styrene

Refernces