methyl O--(2->6)-2,3,4-tri-O-benzyl-α-D-glucopyranoside

Base Information

• Chemical Name: methyl O--(2->6)-2,3,4-tri-O-benzyl-α-D-glucopyranoside
• CAS No.: 90124-30-4
• Molecular Formula: C₄₈H₅₉NO₁₈
• Molecular Weight: 937.992
• Mol file: 90124-30-4.mol

Synonyms:methyl O--(2->6)-2,3,4-tri-O-benzyl-α-D-glucopyranoside

Chemical Property of methyl O--(2->6)-2,3,4-tri-O-benzyl-α-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of methyl O--(2->6)-2,3,4-tri-O-benzyl-α-D-glucopyranoside

There total 26 articles about methyl O--(2->6)-2,3,4-tri-O-benzyl-α-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

methyl 2,3,4-tri-O-benzyl-6-O--α-D-glucopyranoside (108999-05-9) → methyl O--(2->6)-2,3,4-tri-O-benzyl-α-D-glucopyranoside (90124-30-4)

Guidance literature:

With tri-n-butyl-tin hydride; In tetrahydrofuran; at 60 ℃; for 0.5h;

DOI:10.1016/S0040-4020(01)87796-6

Reference yield: 74.0%

methyl 2,3,4-tri-O-benzyl-D-glucopyranoside (53008-65-4,641635-63-4) + methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-D-galacto-2-nonulopyranosonate 2-(N-phenyl)trifluoroacetimidate (874904-90-2) → methyl O--(2->6)-2,3,4-tri-O-benzyl-α-D-glucopyranoside (90124-30-4)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; 3 A molecular sieve; In dichloromethane; at -30 ℃; for 1.5h;

DOI:10.1021/ol0353161

Reference yield: 74.0%

methyl 2,3,4-tri-O-benzyl-D-glucopyranoside (53008-65-4,641635-63-4) + methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-β-D-galacto-2-nonulopyranosonate 2-(N-p-nitrophenyl)trifluoroacetimidate (625824-95-5) → methyl O--(2->6)-2,3,4-tri-O-benzyl-α-D-glucopyranoside (90124-30-4)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; 3 A molecular sieve; In dichloromethane; at -30 ℃;

DOI:10.1021/ol0353161

upstream raw materials:

methyl 2,3,4-tri-O-benzyl-D-glucopyranoside

methyl (methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-D-glycero-β-D-galacto-2-nonulopyranosidonate)

N-acetyl-4,7,8,9-tetra-O-acetyl-2-chloro-2-deoxyneuraminic acid methyl ester

methyl (methyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-2-thio-D-glycero-α-D-galacto-2-nonulopyranosid)onate^10,13