Technology Process of C16H22O5
There total 7 articles about C16H22O5 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
diisobutylaluminium hydride;
In
dichloromethane;
at -80 ℃;
for 1h;
DOI:10.1248/cpb.55.1284
- Guidance literature:
-
((4S,5S)-5-(2-((4-methoxybenzyl)oxy)ethyl)-2,2-dimethyl-1,3-dioxolan-4-yl)methanol;
With
oxalyl dichloride; dimethyl sulfoxide;
In
dichloromethane;
at -78 ℃;
for 1h;
Inert atmosphere;
With
triethylamine;
In
dichloromethane;
at -78 ℃;
for 0.25h;
Inert atmosphere;
DOI:10.1080/00397911.2017.1354381
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: AD-mix β; methanesulfonamide / tert-butyl alcohol; water / 10 h / 0 °C / Inert atmosphere
2.1: toluene-4-sulfonic acid / dichloromethane / 4 h / 0 - 20 °C / Inert atmosphere
3.1: diisobutylaluminium hydride / dichloromethane; toluene / 1 h / 0 - 20 °C / Inert atmosphere
4.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 1 h / -78 °C / Inert atmosphere
4.2: 0.25 h / -78 °C / Inert atmosphere
With
oxalyl dichloride; methanesulfonamide; AD-mix β; diisobutylaluminium hydride; toluene-4-sulfonic acid; dimethyl sulfoxide;
In
dichloromethane; water; toluene; tert-butyl alcohol;
1.1: |Sharpless Dihydroxylation / 4.1: |Swern Oxidation / 4.2: |Swern Oxidation;
DOI:10.1080/00397911.2017.1354381
