5,12-dihydro-5-(3-bromophenyl)-5,12-epoxy-6,11,12-triphenylnaphthacene

Base Information

• Chemical Name: 5,12-dihydro-5-(3-bromophenyl)-5,12-epoxy-6,11,12-triphenylnaphthacene
• CAS No.: 127257-82-3
• Molecular Formula: C₄₂H₂₇BrO
• Molecular Weight: 627.58
• Mol file: 127257-82-3.mol

Synonyms:5,12-dihydro-5-(3-bromophenyl)-5,12-epoxy-6,11,12-triphenylnaphthacene

Chemical Property of 5,12-dihydro-5-(3-bromophenyl)-5,12-epoxy-6,11,12-triphenylnaphthacene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,12-dihydro-5-(3-bromophenyl)-5,12-epoxy-6,11,12-triphenylnaphthacene

There total 4 articles about 5,12-dihydro-5-(3-bromophenyl)-5,12-epoxy-6,11,12-triphenylnaphthacene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

1-(3-bromophenyl)-3-phenylisobenzofuran (127257-59-4) + 2,3-dibromo-1,4-diphenylnaphthalene (127257-79-8) → 5,12-dihydro-5-(3-bromophenyl)-5,12-epoxy-6,11,12-triphenylnaphthacene (127257-82-3)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; -78 deg C -> room temp., 12h;

DOI:10.1021/jo00300a043

Reference yield:

1,3-diphenylisobenzofuran (5471-63-6) → 5,12-dihydro-5-(3-bromophenyl)-5,12-epoxy-6,11,12-triphenylnaphthacene (127257-82-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / p-toluenesulfonic acid / xylene / 4 h / Heating

2: 71 percent / n-BuLi / tetrahydrofuran; hexane / -78 deg C -> room temp., 12h

With n-butyllithium; toluene-4-sulfonic acid; In tetrahydrofuran; hexane; xylene;

DOI:10.1021/jo00300a043

Reference yield:

3-phenylphthalide (5398-11-8) → 5,12-dihydro-5-(3-bromophenyl)-5,12-epoxy-6,11,12-triphenylnaphthacene (127257-82-3)

Guidance literature:

Multi-step reaction with 2 steps

2: 71 percent / n-BuLi / tetrahydrofuran; hexane / -78 deg C -> room temp., 12h

With n-butyllithium; In tetrahydrofuran; hexane;

DOI:10.1021/jo00300a043

upstream raw materials:

1-(3-bromophenyl)-3-phenylisobenzofuran

2,3-dibromo-1,4-diphenylnaphthalene

3-phenylphthalide

1,3-dibromobenzene

Downstream raw materials:

5-(3-bromophenyl)-6,11,12-triphenylnaphthacene