C₂₅H₄₄O₅Si

Base Information

• Chemical Name: C₂₅H₄₄O₅Si
• CAS No.: 947661-52-1
• Molecular Formula: C₂₅H₄₄O₅Si
• Molecular Weight: 452.707
• Mol file: 947661-52-1.mol

Synonyms:C₂₅H₄₄O₅Si

Chemical Property of C₂₅H₄₄O₅Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₄₄O₅Si

There total 15 articles about C₂₅H₄₄O₅Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

C28H48O5Si → C25H44O5Si (947661-52-1)

Guidance literature:

With methanol; camphor-10-sulfonic acid; In dichloromethane; at 0 - 20 ℃; for 0.5h;

DOI:10.1016/j.tetlet.2007.05.021

Reference yield:

C13H17O2I (947661-40-7) → C25H44O5Si (947661-52-1)

Guidance literature:

Multi-step reaction with 14 steps

1.1: 82 percent / Zn; NaI / methanol / 4 h / Heating

2.1: 85 percent / N-bromosuccinimide / CH₂Cl₂ / 1 h / 0 - 20 °C

3.1: 86 percent / (n-Bu)3SnH; AIBN / benzene / 0.5 h / Heating

4.1: 83 percent / CrO₃; aq. H₂SO₄ / acetone / 1 h / 0 - 20 °C

5.1: 82 percent / triphenylphosphine / tetrahydrofuran / 3 h / Heating

6.1: 80 percent / Li sand / tetrahydrofuran / 2 h / Heating

7.1: 84 percent / imidazole / CH₂Cl₂ / 12 h / 0 - 20 °C

8.1: n-BuLi; BF₃*OEt₂ / tetrahydrofuran / -78 °C

8.2: 88 percent / tetrahydrofuran / -78 °C

9.1: 77 percent / LiAlH₄ / bis-(2-methoxy-ethyl) ether; tetrahydrofuran / 6 h / 155 °C

10.1: 82 percent / CSA / acetone / 1 h / 0 - 20 °C

11.1: 87 percent / Et₃N; DMAP / CH₂Cl₂ / 12 h / 0 - 20 °C

12.1: 79 percent / AD-mix-β; CH3SO2NH2 / 2-methyl-propan-2-ol; H2O / 0 - 20 °C

13.1: 90 percent / 2,6-lutidine / CH₂Cl₂ / 0.5 h / 0 - 20 °C

14.1: 88 percent / methanol; CSA / CH₂Cl₂ / 0.5 h / 0 - 20 °C

With 1H-imidazole; 2,6-dimethylpyridine; chromium(VI) oxide; methanol; dmap; N-Bromosuccinimide; lithium aluminium tetrahydride; n-butyllithium; 2,2'-azobis(isobutyronitrile); methanesulfonamide; AD-mix-β; sulfuric acid; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; tri-n-butyl-tin hydride; lithium; triethylamine; triphenylphosphine; sodium iodide; zinc; camphor-10-sulfonic acid; In tetrahydrofuran; methanol; dichloromethane; diethylene glycol dimethyl ether; water; acetone; tert-butyl alcohol; benzene; 4.1: Jones' oxidation;

DOI:10.1016/j.tetlet.2007.05.021

Reference yield:

C17H26O3 → C25H44O5Si (947661-52-1)

Guidance literature:

Multi-step reaction with 11 steps

1.1: 83 percent / CrO₃; aq. H₂SO₄ / acetone / 1 h / 0 - 20 °C

2.1: 82 percent / triphenylphosphine / tetrahydrofuran / 3 h / Heating

3.1: 80 percent / Li sand / tetrahydrofuran / 2 h / Heating

4.1: 84 percent / imidazole / CH₂Cl₂ / 12 h / 0 - 20 °C

5.1: n-BuLi; BF₃*OEt₂ / tetrahydrofuran / -78 °C

5.2: 88 percent / tetrahydrofuran / -78 °C

6.1: 77 percent / LiAlH₄ / bis-(2-methoxy-ethyl) ether; tetrahydrofuran / 6 h / 155 °C

7.1: 82 percent / CSA / acetone / 1 h / 0 - 20 °C

8.1: 87 percent / Et₃N; DMAP / CH₂Cl₂ / 12 h / 0 - 20 °C

9.1: 79 percent / AD-mix-β; CH3SO2NH2 / 2-methyl-propan-2-ol; H2O / 0 - 20 °C

10.1: 90 percent / 2,6-lutidine / CH₂Cl₂ / 0.5 h / 0 - 20 °C

11.1: 88 percent / methanol; CSA / CH₂Cl₂ / 0.5 h / 0 - 20 °C

With 1H-imidazole; 2,6-dimethylpyridine; chromium(VI) oxide; methanol; dmap; lithium aluminium tetrahydride; n-butyllithium; methanesulfonamide; AD-mix-β; sulfuric acid; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; lithium; triethylamine; triphenylphosphine; camphor-10-sulfonic acid; In tetrahydrofuran; dichloromethane; diethylene glycol dimethyl ether; water; acetone; tert-butyl alcohol; 1.1: Jones' oxidation;

DOI:10.1016/j.tetlet.2007.05.021

upstream raw materials:

C₁₃H₁₇O₂I

C₁₇H₂₅O₃Br

C₁₆H₂₀O₂Cl₂

C₂₁H₄₄O₂Si₂

Downstream raw materials:

C₂₆H₄₄O₄Si

C₃₂H₅₈O₄Si₂

C₃₂H₅₈O₅Si₂

C₅₀H₈₆O₈Si₃