4-(4-Dimethylaminostyryl)quinoline

Base Information

• Chemical Name: 4-(4-Dimethylaminostyryl)quinoline
• CAS No.: 897-55-2
• Deprecated CAS: 66796-38-1,82735-46-4,82735-46-4
• Molecular Formula: C19H18 N2
• Molecular Weight: 274.39
• Hs Code.: 2933499090
• NSC Number: 4236
• UNII: 68S3S367YF
• DSSTox Substance ID: DTXSID2061270
• Nikkaji Number: J54.280F
• Wikidata: Q27264272
• Metabolomics Workbench ID: 125248
• ChEMBL ID: CHEMBL1884481
• Mol file: 897-55-2.mol

Synonyms:4-(4-DIMETHYLAMINOSTYRYL)QUINOLINE;897-55-2;4-(p-Dimethylaminostyryl)quinoline;4M20;NSC-4236;X 87;N,N-Dimethyl-4-(2-(quinolin-4-yl)vinyl)aniline;4-(p-(Dimethylamino)styryl)quinoline;Quinoline, 4-(p-(dimethylamino)styryl)-;Quinoline, 4-[p-(dimethylamino)styryl]-;Benzenamine, N,N-dimethyl-4-(2-(4-quinolinyl)ethenyl)-;NSC4236;68S3S367YF;Benzenamine, N,N-dimethyl-4-[2-(4-quinolinyl)ethenyl]-;N,N-dimethyl-4-[(E)-2-(4-quinolyl)vinyl]aniline;N,N-dimethyl-N-{4-[2-(4-quinolinyl)vinyl]phenyl}amine;4-[p-(Dimethylamino)styryl]quinoline;2-(4-N,N-(Dimethylamino)styryl)quinoline;2-[4-N,N-(Dimethylamino)styryl]quinoline;HSDB 5518;NSC 4236;N,N-dimethyl-4-[(E)-2-quinolin-4-ylethenyl]aniline;2-(4-N,N-Dimethylaminostyryl)quinoline;UNII-68S3S367YF;AI3-26406;4-(4-Dimethylaminostyryl)quinoline ,;Cambridge id 5271717;4M2O;CHEMBL1884481;DTXSID2061270;CIXDQQGMRYRUQA-JXMROGBWSA-N;4-[p-Dimethylamino]styrylquinoline;NSC 10482;4-[4-(Dimethylamino)styryl]quinoline;AKOS015850774;NK-1837;Quinoline, 4-(p-dimethylaminostyryl)-;WLN: T66 BNJ E1U1R DN1&1;NCGC00184045-01;NCGC00184045-02;NCGC00184045-03;NCGC00184045-04;NCGC00184045-05;NCGC00184045-06;NCGC00184045-07;NCGC00184045-08;NCGC00184045-09;NCGC00184045-10;NCGC00184045-11;NCGC00184045-12;NCGC00184045-13;NCGC00184045-14;NCGC00184045-15;NCGC00184045-16;NCGC00184045-17;NCGC00184045-18;NCGC00184045-19;NCGC00184045-20;NCGC00184045-21;NCGC00184045-22;NCGC00184045-23;NCGC00184045-24;NCGC00184045-25;NCGC00184045-26;NCGC00184045-27;NCGC00184045-28;NCGC00184045-29;Quinoline, 4-(4-N,N-dimethylaminostyryl);DIMETHYLAMINOSTYRYL)QUINOLINE, 4-(P-;AB00078544-01;4-(4-DIMETHYLAMINOSTYRYL)QUINOLINE [HSDB];A843298;AE-848/00962031;(E)-N,N-dimethyl-4-(2-(quinolin-4-yl)vinyl)aniline;Benzenamine,N-dimethyl-4-[2-(4-quinolinyl)ethenyl]-;Q27264272;Z57957552;N,N-Dimethyl-4-[(E)-2-(4-quinolinyl)ethenyl]aniline #

Chemical Property of 4-(4-Dimethylaminostyryl)quinoline

Chemical Property:

• Vapor Pressure: 1.13E-08mmHg at 25°C
• Melting Point: 140 °C
• Refractive Index: 1.8676 (estimate)
• Boiling Point: 460.8ºC at 760 mmHg
• Flash Point: 232.5ºC
• PSA: 16.13000
• Density: 1.152g/cm3
• LogP: 4.47120
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 274.146998583
• Heavy Atom Count: 21
• Complexity: 342

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-(4-Dimethylaminostyryl)quinoline >96.0%(HPLC)(T) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=CC=C(C=C1)C=CC2=CC=NC3=CC=CC=C23
• Isomeric SMILES: CN(C)C1=CC=C(C=C1)/C=C/C2=CC=NC3=CC=CC=C23

Technology Process of 4-(4-Dimethylaminostyryl)quinoline

There total 3 articles about 4-(4-Dimethylaminostyryl)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C6H4NCH2CHCCH2 (491-35-0) → quinoline-vinyl-N,N-dimethylaniline (897-55-2)

Guidance literature:

Multi-step reaction with 3 steps

1: acetonitrile / 12 h / 90 °C

2: piperidine / ethanol / 6 h / 70 °C

3: dihydrogen peroxide

With piperidine; dihydrogen peroxide; In ethanol; acetonitrile;

Reference yield:

C32H36BN2O2(1+)*Br(1-) → quinoline-vinyl-N,N-dimethylaniline (897-55-2)

Guidance literature:

With dihydrogen peroxide;

DOI:10.1002/anie.202005959

Reference yield:

C32H36BN2O2(1+) → quinoline-vinyl-N,N-dimethylaniline (897-55-2)

Guidance literature:

With dihydrogen peroxide;

upstream raw materials:

C₆H₄NCH₂CHCCH₂

Refernces

• 1、 -. "Monomolecular fluorescent probe for simultaneous super-resolution imaging of mitochondrial hydrogen peroxide, proteins and nucleic acids as well as preparation and application of monomolecular fluorescent probe". . . Retrieved 2020/04/01.