N,N'-bis(2,6-diisopropylphenyl)-N-formylethylenediamine

Base Information

• Chemical Name: N,N'-bis(2,6-diisopropylphenyl)-N-formylethylenediamine
• CAS No.: 1096001-27-2
• Molecular Formula: C₂₇H₄₀N₂O
• Molecular Weight: 408.627
• Mol file: 1096001-27-2.mol

Synonyms:N,N'-bis(2,6-diisopropylphenyl)-N-formylethylenediamine

Chemical Property of N,N'-bis(2,6-diisopropylphenyl)-N-formylethylenediamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of N,N'-bis(2,6-diisopropylphenyl)-N-formylethylenediamine

There total 3 articles about N,N'-bis(2,6-diisopropylphenyl)-N-formylethylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

N,N'-dimethylbenzylamine (103-83-3) + palladium dichloride + 1,3-bis[(2,6-diisopropyl)phenyl]imidazolinium chloride (258278-25-0) → N,N'-bis(2,6-diisopropylphenyl)-N-formylethylenediamine (1096001-27-2) + (1,3-bis(2,6-diisopropylphenyl)-4,5-dihydroimidazolyl-2-ylidene)Pd(N,N-dimethylbenzylamine(-1H)-κ2N,C)Cl

Guidance literature:

With Cs₂CO₃; In acetonitrile; High Pressure; MeCN, amine and molecular sieves (4?) added to PdCl2; stirred at 80°C until complete dissolution; finely powdered Cs2CO3 (2.5 equiv.)added; heated (80°C, 5 min); dihydroimidazolium salt added; heat ed with stirring (80°C, 18 h); filtered through Celite (CH2Cl2); volatiles removed; purified by flash chromy. (silica gel, hexane-CH2Cl2 (9:1) in ethyl acetate from 0% to 40% (20 min)); elem. anal.;

DOI:10.1021/om8008475

Reference yield: 61.0%

1,3-bis(2,6-diisopropylphenyl)dihydroimidazol-2-ylidene (258278-28-3) → N,N'-bis(2,6-diisopropylphenyl)-N-formylethylenediamine (1096001-27-2)

Guidance literature:

With oxygen; In tetrahydrofuran; for 5h; Schlenk technique; Inert atmosphere;

DOI:10.1039/c8cc08911f

Reference yield:

(SIPr)Cu(OAc)2 → N,N'-bis(2,6-diisopropylphenyl)-N-formylethylenediamine (1096001-27-2)

Guidance literature:

With water; In chloroform; Inert atmosphere;

DOI:10.1039/c0dt01630f

upstream raw materials:

N,N'-dimethylbenzylamine

1,3-bis[(2,6-diisopropyl)phenyl]imidazolinium chloride

1,3-bis(2,6-diisopropylphenyl)dihydroimidazol-2-ylidene