1-Cyclohexylpropan-1-amine

Base Information

• Chemical Name: 1-Cyclohexylpropan-1-amine
• CAS No.: 854750-32-6
• Molecular Formula: C₉H₁₉N
• Molecular Weight: 141.257
• European Community (EC) Number: 852-621-9,936-209-7
• Mol file: 854750-32-6.mol

Synonyms:1-cyclohexylpropan-1-amine;854750-32-6;SCHEMBL2257328;UJAHMMDIDKVNLK-UHFFFAOYSA-N;AKOS008141529;AB92203;EN300-62855;G45254;Z513797596

Chemical Property of 1-Cyclohexylpropan-1-amine

Chemical Property:

• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 141.151749610
• Heavy Atom Count: 10
• Complexity: 84.7

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCC(C1CCCCC1)N

Technology Process of 1-Cyclohexylpropan-1-amine

There total 2 articles about 1-Cyclohexylpropan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 27.0%

cyclohexyl ethyl ketone (1123-86-0) → 1-cyclohexylpropan-1-amine (854750-32-6)

Guidance literature:

With ammonium acetate; sodium cyanoborohydride; In methanol; Reflux;

Reference yield:

1-phenylpropylamine (2941-20-0) → 1-cyclohexylpropan-1-amine (854750-32-6)

Guidance literature:

With ethanol; nickel; at 160 - 170 ℃; under 73550.8 Torr; Hydrogenation;

Reference yield: 38.0%

3-iodo-1H-indazole-5-carboxylic acid (885521-46-0) + 1-cyclohexylpropan-1-amine (854750-32-6) → N-(1-cyclohexylpropyl)-3-iodo-1H-indazole-5-carboxamide (1430472-97-1)

Guidance literature:

With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 0 ℃; for 1h;

upstream raw materials:

1-phenylpropylamine

cyclohexyl ethyl ketone

Downstream raw materials:

N-(1-cyclohexylpropyl)-3-iodo-1H-indazole-5-carboxamide