prop-2-enyl 1-(4-tolyl)-2,14-dioxo-1-azacyclotetradecane-3-carboxylate

Base Information

• Chemical Name: prop-2-enyl 1-(4-tolyl)-2,14-dioxo-1-azacyclotetradecane-3-carboxylate
• CAS No.: 307493-17-0
• Molecular Formula: C₂₄H₃₃NO₄
• Molecular Weight: 399.53
• Mol file: 307493-17-0.mol

Synonyms:prop-2-enyl 1-(4-tolyl)-2,14-dioxo-1-azacyclotetradecane-3-carboxylate

Chemical Property of prop-2-enyl 1-(4-tolyl)-2,14-dioxo-1-azacyclotetradecane-3-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of prop-2-enyl 1-(4-tolyl)-2,14-dioxo-1-azacyclotetradecane-3-carboxylate

There total 1 articles about prop-2-enyl 1-(4-tolyl)-2,14-dioxo-1-azacyclotetradecane-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

2-Oxocyclododecan-1-carbonsaeure-allylester (97416-37-0) + p-Tolylisocyanate (622-58-2,374675-64-6) → prop-2-enyl 1-(4-tolyl)-2,14-dioxo-1-azacyclotetradecane-3-carboxylate (307493-17-0)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1002/1522-2675(20000809)83:8<1809::AID-HLCA1809>3.0.CO;2-L

Reference yield: 80.0%

prop-2-enyl 1-(4-tolyl)-2,14-dioxo-1-azacyclotetradecane-3-carboxylate (307493-17-0) → 1-(4-tolyl)-1-azacyclotetradecane-2,14-dione (307493-18-1)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; formic acid; triethylamine; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1002/1522-2675(20000809)83:8<1809::AID-HLCA1809>3.0.CO;2-L

upstream raw materials:

2-Oxocyclododecan-1-carbonsaeure-allylester

p-Tolylisocyanate

Downstream raw materials:

1-(4-tolyl)-1-azacyclotetradecane-2,14-dione