Technology Process of 5-(3-iodo-1-tosyl-1H-indol-5-yl)-1,3,4-thiadiazol-2-amine
There total 3 articles about 5-(3-iodo-1-tosyl-1H-indol-5-yl)-1,3,4-thiadiazol-2-amine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
5-(3-iodo-1-tosyl-1H-indol-5-yl)-N-(4-methoxybenzyl)-1,3,4-thiadiazol-2-amine;
With
trifluoroacetic acid;
at 100 ℃;
for 0.133333h;
Microwave irradiation;
With
sodium hydrogencarbonate;
In
dichloromethane;
- Guidance literature:
-
Multi-step reaction with 5 steps
1: potassium hydroxide; iodine / N,N-dimethyl-formamide / 2 h / 20 °C
2: sodium hydride / N,N-dimethyl-formamide; mineral oil / 8 h / 20 °C
3: sodium tungstate; dihydrogen peroxide / water; acetic acid / 72 h / 20 °C
4: 1,4-dioxane / 20 - 100 °C
5: trifluoroacetic acid / 0.13 h / 100 °C / Microwave irradiation
With
sodium tungstate; dihydrogen peroxide; iodine; sodium hydride; trifluoroacetic acid; potassium hydroxide;
In
1,4-dioxane; water; acetic acid; N,N-dimethyl-formamide; mineral oil;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 8 h / 20 °C
2: sodium tungstate; dihydrogen peroxide / water; acetic acid / 72 h / 20 °C
3: 1,4-dioxane / 20 - 100 °C
4: trifluoroacetic acid / 0.13 h / 100 °C / Microwave irradiation
With
sodium tungstate; dihydrogen peroxide; sodium hydride; trifluoroacetic acid;
In
1,4-dioxane; water; acetic acid; N,N-dimethyl-formamide; mineral oil;
