2-(3,4-dihydro-7-methoxybenzopyran-3-yl)-6-phenylthio-1,4-benzoquinone

Base Information

• Chemical Name: 2-(3,4-dihydro-7-methoxybenzopyran-3-yl)-6-phenylthio-1,4-benzoquinone
• CAS No.: 550337-69-4
• Molecular Formula: C₂₂H₁₈O₄S
• Molecular Weight: 378.449
• Mol file: 550337-69-4.mol

Synonyms:2-(3,4-dihydro-7-methoxybenzopyran-3-yl)-6-phenylthio-1,4-benzoquinone

Chemical Property of 2-(3,4-dihydro-7-methoxybenzopyran-3-yl)-6-phenylthio-1,4-benzoquinone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-(3,4-dihydro-7-methoxybenzopyran-3-yl)-6-phenylthio-1,4-benzoquinone

There total 2 articles about 2-(3,4-dihydro-7-methoxybenzopyran-3-yl)-6-phenylthio-1,4-benzoquinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3,4-dihydro-7-methoxybenzopyran-3-yl)-1,4-benzoquinone (69618-76-4) + thiophenol (108-98-5) → 2-(3,4-dihydro-7-methoxybenzopyran-3-yl)-6-phenylthio-1,4-benzoquinone (550337-69-4) + 2-(3,4-dihydro-7-methoxybenzopyran-3-yl)-5-phenylthio-1,4-benzoquinone (550337-71-8)

Guidance literature:

(3,4-dihydro-7-methoxybenzopyran-3-yl)-1,4-benzoquinone; thiophenol; With toluene-4-sulfonic acid; In methanol; at 25 ℃; for 7h;

With sodium sulfate; silver(l) oxide; In benzene; at 25 ℃; for 4h;

DOI:10.1021/jo030026j

Reference yield:

p-benzoquinone (106-51-4) → 2-(3,4-dihydro-7-methoxybenzopyran-3-yl)-6-phenylthio-1,4-benzoquinone (550337-69-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: BH₃*THF / tetrahydrofuran / 5 h / 20 °C

1.2: 37 percent / air / tetrahydrofuran; H₂O / 2 h / 20 °C

2.1: p-toluenesulfonic acid hydrate / methanol / 7 h / 25 °C

2.2: Ag₂O; Na₂SO₄ / benzene / 4 h / 25 °C

With borane-THF; toluene-4-sulfonic acid; In tetrahydrofuran; methanol;

DOI:10.1021/jo030026j

Reference yield: 96.0%

2-(3,4-dihydro-7-methoxybenzopyran-3-yl)-6-phenylthio-1,4-benzoquinone (550337-69-4) → 2-benzenesulfinyl-6-(7-methoxy-chroman-3-yl)-[1,4]benzoquinone

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In chloroform; at 0 ℃; for 1h;

DOI:10.1021/jo030026j

upstream raw materials:

(3,4-dihydro-7-methoxybenzopyran-3-yl)-1,4-benzoquinone

thiophenol

p-benzoquinone