cyclopenta-1,3-dienyl-(1S,2S,5R)-4-methyl-1-(prop-2-yl)-cyclohexane

Base Information

• Chemical Name: cyclopenta-1,3-dienyl-(1S,2S,5R)-4-methyl-1-(prop-2-yl)-cyclohexane
• CAS No.: 891826-22-5
• Molecular Formula: C₁₅H₂₄
• Molecular Weight: 204.356
• Mol file: 891826-22-5.mol

Synonyms:cyclopenta-1,3-dienyl-(1S,2S,5R)-4-methyl-1-(prop-2-yl)-cyclohexane

Chemical Property of cyclopenta-1,3-dienyl-(1S,2S,5R)-4-methyl-1-(prop-2-yl)-cyclohexane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cyclopenta-1,3-dienyl-(1S,2S,5R)-4-methyl-1-(prop-2-yl)-cyclohexane

There total 3 articles about cyclopenta-1,3-dienyl-(1S,2S,5R)-4-methyl-1-(prop-2-yl)-cyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

(1S,2S,5R)-methane sulfonic acid-[(5-methyl-2-prop-2-yl)-cyclohexyl-1-yl]-ester + cyclopenta-1,3-diene (542-92-7,25568-84-7,7313-32-8) → cyclopenta-1,3-dienyl-(1S,2S,5R)-4-methyl-1-(prop-2-yl)-cyclohexane (891826-22-5)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 0 - 20 ℃; for 24h;

DOI:10.1016/j.jorganchem.2005.10.026

Reference yield:

Neomenthol (2216-52-6) → cyclopenta-1,3-dienyl-(1S,2S,5R)-4-methyl-1-(prop-2-yl)-cyclohexane (891826-22-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / pyridine / 15 h / 2 °C

2: 77 percent / NaH / tetrahydrofuran / 24 h / 0 - 20 °C

With sodium hydride; In tetrahydrofuran; pyridine;

DOI:10.1016/j.jorganchem.2005.10.026

Reference yield:

(1S,2S,5R)-(+)-2-isopropyl-5-methylcyclohexyl tosylate (2230-82-2,2230-91-3,7212-65-9,14539-75-4,14539-76-5,60183-51-9,63559-37-5,2230-77-5) + sodium cyclopentadienylide (4984-82-1) → cyclopenta-1,3-dienyl-(1S,2S,5R)-4-methyl-1-(prop-2-yl)-cyclohexane (891826-22-5)

Guidance literature:

In tetrahydrofuran; for 14h; Yield given; Ambient temperature;

DOI:10.1021/ja982868j

upstream raw materials:

(1S,2S,5R)-(+)-2-isopropyl-5-methylcyclohexyl tosylate

sodium cyclopentadienylide

cyclopenta-1,3-diene

Neomenthol