Dpt-prostaglandin E1

Base Information

• Chemical Name: Dpt-prostaglandin E1
• CAS No.: 80558-61-8
• Molecular Formula: C₂₂H₃₀O₅
• Molecular Weight: 374.477
• UNII: 70K4BF31QF
• Nikkaji Number: J449.332J
• Wikidata: Q27083667
• Pharos Ligand ID: VP67BLAMVFAG
• Mol file: 80558-61-8.mol

Synonyms:11-deoxy-16-phenoxy-17,18,19,20-tetranor-PGE1;11-deoxy-16-phenoxy-17,18,19,20-tetranorprostaglandin E1;DPT-prostaglandin E1;M and B 28,767;M and B 28767;M and B-28767;M and B28767;MB-28767

Chemical Property of Dpt-prostaglandin E1

Chemical Property:

• Vapor Pressure: 2.03E-14mmHg at 25°C
• Boiling Point: 582.7°C at 760 mmHg
• Flash Point: 200°C
• PSA: 83.83000
• Density: 1.175g/cm³
• LogP: 4.00300
• XLogP3: 3.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 12
• Exact Mass: 374.20932405
• Heavy Atom Count: 27
• Complexity: 481

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC(=O)C(C1C=CC(COC2=CC=CC=C2)O)CCCCCCC(=O)O
• Isomeric SMILES: C1CC(=O)[C@@H]([C@H]1/C=C/[C@H](COC2=CC=CC=C2)O)CCCCCCC(=O)O

Technology Process of Dpt-prostaglandin E1

There total 5 articles about Dpt-prostaglandin E1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

7-[(1R,2R)-2-((E)-(R)-3-Hydroxy-4-phenoxy-but-1-enyl)-5-oxo-cyclopentyl]-heptanoic acid methyl ester (122518-43-8) → 15S-hydroxy-9-oxo-16-phenoxy-ω-tetranorprost-13E-enoic acid (80558-61-8)

Guidance literature:

With potassium hydroxide; In methanol; for 2h; Ambient temperature;

DOI:10.1007/BF00770628

Reference yield:

→ 7-[2-((E)-3-Hydroxy-4-phenoxy-but-1-enyl)-5-oxo-cyclopentyl]-heptanoic acid (60972-43-2,61009-32-3,80558-61-8,90319-21-4)

Guidance literature:

entspr. 1,4-Dioxa-spiro-<4,4>-nonan-Verb., Hydrolyse;

Reference yield:

→ 7-[(R)-2-((E)-3-Hydroxy-4-phenoxy-but-1-enyl)-5-oxo-cyclopentyl]-heptanoic acid (60972-43-2,61009-32-3,80558-61-8,90319-21-4)

Guidance literature:

analog den Vorschriften in den Exx. 1-6;

upstream raw materials:

7-[(1R,2R)-2-((E)-(R)-3-Hydroxy-4-phenoxy-but-1-enyl)-5-oxo-cyclopentyl]-heptanoic acid methyl ester

Refernces