Loxiglumide

Base Information

• Chemical Name: Loxiglumide
• CAS No.: 107097-80-3
• Molecular Formula: C21H30 Cl2 N2 O5
• Molecular Weight: 461.386
• Hs Code.: 2924299090
• European Community (EC) Number: 687-542-7
• UNII: 77MPX3N42I
• DSSTox Substance ID: DTXSID6057615
• Wikidata: Q27081501
• NCI Thesaurus Code: C96872
• Pharos Ligand ID: 8RV26T5142J7
• ChEMBL ID: CHEMBL206025
• Mol file: 107097-80-3.mol

Synonyms:4-(3,4-dichlorobenzoylamino)-5-(N-3-methoxypropylpentylamino)-5-oxopentanoic acid;CR 1505;CR-1505;loxiglumide

Chemical Property of Loxiglumide

Chemical Property:

• Vapor Pressure: 7.51E-17mmHg at 25°C
• Melting Point: 113-115℃
• Boiling Point: 632.2°Cat760mmHg
• PKA: pKa ~5(at 25℃)
• Flash Point: 336.1°C
• PSA: 95.94000
• Density: 1.233g/cm³
• LogP: 4.40280
• Storage Temp.: 2-8°C
• Solubility.: DMSO: ≥5mg/mL
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 14
• Exact Mass: 460.1531774
• Heavy Atom Count: 30
• Complexity: 550

Purity/Quality:

98%,99%, ^*data from raw suppliers

Loxiglumide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Moderately toxic by ingestion.
• Hazard Codes: Xn
• Statements: 22

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCN(CCCOC)C(=O)C(CCC(=O)O)NC(=O)C1=CC(=C(C=C1)Cl)Cl
• Uses: Loxiglumide is a CCK1 antagonist. Suppresses CCK-induced proliferation of acinar cells. Inhibits pancreatic secretion of digestive enzymes. Active in vivo.