Technology Process of C48H58N14O12
There total 11 articles about C48H58N14O12 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
4-methyl-morpholine; bromo-tris-dimethylamino-phosphonium hexafluorophosphate;
In
N,N-dimethyl-formamide;
DOI:10.1016/0040-4039(96)00037-8
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1.) HOSu, DCC, 2.) NMM / 1.) DMF, room temperature, 12 h, 2.) DMF, -15 deg C (3 h), room temperature (2 h)
2: Et3N, Brop / CH2Cl2 / 2 h / Ambient temperature
With
4-methyl-morpholine; 1-hydroxy-pyrrolidine-2,5-dione; bromo-tris-dimethylamino-phosphonium hexafluorophosphate; triethylamine; dicyclohexyl-carbodiimide;
In
dichloromethane;
DOI:10.1016/S0040-4020(98)01211-3
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 57 percent / DMAP / dimethylformamide
2: 83 percent / LiOH / dioxane; H2O
3: 1.) triphenyl phosphine, N-bromosucciniomide; 2.) N-methylmorpholine / 1.) CH2Cl2
4: 100 percent / tetrakis(triphenyl phosphine)palladium, morpholine / tetrahydrofuran
5: 1.) DCC, HOSu; 2.) NMM / 1.) CH2Cl2, 18 h; 2.) -15 degC
6: 80 percent / Brop, NMM / dimethylformamide
With
morpholine; 4-methyl-morpholine; dmap; lithium hydroxide; 1-hydroxy-pyrrolidine-2,5-dione; N-Bromosuccinimide; tetrakis(triphenylphosphine) palladium(0); bromo-tris-dimethylamino-phosphonium hexafluorophosphate; dicyclohexyl-carbodiimide; triphenylphosphine;
In
tetrahydrofuran; 1,4-dioxane; water; N,N-dimethyl-formamide;
DOI:10.1016/0040-4039(96)00037-8
