(R)-tert-butyl 3-(4-amino-3-(4-aminophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)pyrrolidine-1-arboxylate

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Chemical Name:(R)-tert-butyl 3-(4-amino-3-(4-aminophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)pyrrolidine-1-arboxylate
CAS No.:1221743-87-8
Molecular Formula:C₂₀H₂₅N₇O₂
Molecular Weight:395.464
Hs Code.:

Synonyms:(R)-tert-butyl 3-(4-amino-3-(4-aminophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)pyrrolidine-1-arboxylate

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Chemical Property of (R)-tert-butyl 3-(4-amino-3-(4-aminophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)pyrrolidine-1-arboxylate

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Technology Process of (R)-tert-butyl 3-(4-amino-3-(4-aminophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)pyrrolidine-1-arboxylate

There total 1 articles about (R)-tert-butyl 3-(4-amino-3-(4-aminophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)pyrrolidine-1-arboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1221743-88-9
(R)-tert-butyl 3-(4-amino-3-(4-nitrophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)pyrrolidine-1-carboxylate

: 1221743-87-8
(R)-tert-butyl 3-(4-amino-3-(4-aminophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)pyrrolidine-1-arboxylate

Guidance literature:: With acetic acid; zinc; In tetrahydrofuran; at 20 ℃; for 12h; Inert atmosphere;

Reference yield:

: 1221743-87-8
(R)-tert-butyl 3-(4-amino-3-(4-aminophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)pyrrolidine-1-arboxylate

: 329-01-1
1-isocyanato-3-trifluoromethyl-benzene

: 1221743-89-0
1-(4-(4-amino-1-((R)-pyrrolidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)phenyl)-3-(3-(trifluoromethyl)phenyl)urea

: 1221743-90-3
(R)-3-(4-amino-3-(4-aminophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-N-(3-(trifluoromethyl)phenyl)pyrrolidine-1-carboxamide

: 1221743-91-4
(R)-3-(4-amino-3-(4-(3-(3-(trifluoromethyl)phenyl)ureido)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)-N-(3-(trifluoromethyl)phenyl)pyrrolidine-1-carboxamide

Guidance literature:: (R)-tert-butyl 3-(4-amino-3-(4-aminophenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)pyrrolidine-1-arboxylate; 1-isocyanato-3-trifluoromethyl-benzene; In dichloromethane; at 20 ℃; Cooling with ice;

With hydrogenchloride; formic acid; water; In dichloromethane; for 12h;