N⁴-(2-Diethylamino-ethyl)-N²-[4-(4-methyl-piperazin-1-yl)-phenyl]-quinazoline-2,4-diamine; hydrochloride

Base Information

• Chemical Name: N⁴-(2-Diethylamino-ethyl)-N²-[4-(4-methyl-piperazin-1-yl)-phenyl]-quinazoline-2,4-diamine; hydrochloride
• CAS No.: 76004-83-6
• Molecular Formula: C₂₅H₃₅N₇*3ClH
• Molecular Weight: 542.983
• Mol file: 76004-83-6.mol

Synonyms:N⁴-(2-Diethylamino-ethyl)-N²-[4-(4-methyl-piperazin-1-yl)-phenyl]-quinazoline-2,4-diamine; hydrochloride

Chemical Property of N⁴-(2-Diethylamino-ethyl)-N²-[4-(4-methyl-piperazin-1-yl)-phenyl]-quinazoline-2,4-diamine; hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of N⁴-(2-Diethylamino-ethyl)-N²-[4-(4-methyl-piperazin-1-yl)-phenyl]-quinazoline-2,4-diamine; hydrochloride

There total 1 articles about N⁴-(2-Diethylamino-ethyl)-N²-[4-(4-methyl-piperazin-1-yl)-phenyl]-quinazoline-2,4-diamine; hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

4-(4-Methyl-piperazino)-anilin (16153-81-4) + N,N-diethyl-N'-(2-chloro-quinazolin-4-yl)-ethane-1,2-diamine (76004-37-0) → N4-(2-Diethylamino-ethyl)-N2-[4-(4-methyl-piperazin-1-yl)-phenyl]-quinazoline-2,4-diamine; hydrochloride (76004-83-6)

Guidance literature:

With hydrogenchloride; In ethanol; for 3h; Heating;

DOI:10.1021/jm00134a002

upstream raw materials:

4-(4-Methyl-piperazino)-anilin

N,N-diethyl-N'-(2-chloro-quinazolin-4-yl)-ethane-1,2-diamine