N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-(2-{2-[2-(2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethylamino}-phenoxy)-phenylamino]-ethoxy}-ethoxy)-acetamide

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Chemical Name:N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-(2-{2-[2-(2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethylamino}-phenoxy)-phenylamino]-ethoxy}-ethoxy)-acetamide
CAS No.:181725-61-1
Molecular Formula:C₅₄H₆₀N₆O₁₃
Molecular Weight:1001.1
Hs Code.:

N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-(2-{2-[2-(2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethylamino}-phenoxy)-phenylamino]-ethoxy}-ethoxy)-acetamide

Synonyms:N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-(2-{2-[2-(2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethylamino}-phenoxy)-phenylamino]-ethoxy}-ethoxy)-acetamide

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Chemical Property of N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-(2-{2-[2-(2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethylamino}-phenoxy)-phenylamino]-ethoxy}-ethoxy)-acetamide

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Technology Process of N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-(2-{2-[2-(2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethylamino}-phenoxy)-phenylamino]-ethoxy}-ethoxy)-acetamide

There total 13 articles about N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-(2-{2-[2-(2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethylamino}-phenoxy)-phenylamino]-ethoxy}-ethoxy)-acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 181725-59-7
2-{2-[2-(Benzyl-{2-[2-(benzyl-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethyl}-amino)-phenoxy]-phenyl}-amino)-ethoxy]-ethoxy}-N-{2-[2-(2-methoxy-acetylamino)-phenoxy]-phenyl}-acetamide

: 181725-61-1
N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-(2-{2-[2-(2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethylamino}-phenoxy)-phenylamino]-ethoxy}-ethoxy)-acetamide

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; for 16h; Ambient temperature;
DOI:10.1055/s-1996-4319

Reference yield:

: 24878-25-9
bis(2-aminophenyl)ether

: 181725-61-1
N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-(2-{2-[2-(2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethylamino}-phenoxy)-phenylamino]-ethoxy}-ethoxy)-acetamide

Guidance literature:: Multi-step reaction with 3 steps

1: 48 percent / Et₃N / CH₂Cl₂ / 16 h / Ambient temperature

2: 68 percent / Et₃N / CH₂Cl₂ / 2 h / Heating

3: 100 percent / H₂ / 10percent Pd/C / ethanol / 16 h / Ambient temperature

With hydrogen; triethylamine; palladium on activated charcoal; In ethanol; dichloromethane;
DOI:10.1055/s-1996-4319

Reference yield:

: 88-75-5,78813-12-4
2-hydroxynitrobenzene

: 181725-61-1
N-{2-[2-(2-Methoxy-acetylamino)-phenoxy]-phenyl}-2-(2-{2-[2-(2-{2-[2-({2-[2-(2-methoxy-acetylamino)-phenoxy]-phenylcarbamoyl}-methoxy)-ethoxy]-ethylamino}-phenoxy)-phenylamino]-ethoxy}-ethoxy)-acetamide

Guidance literature:: Multi-step reaction with 5 steps

1: 77 percent / K₂CO₃ / dimethylsulfoxide / 16 h / 95 °C

2: 80 percent / NH₂NH₂*H₂O / 10percent Pd/C / ethanol / 1 h / Heating

3: 48 percent / Et₃N / CH₂Cl₂ / 16 h / Ambient temperature

4: 68 percent / Et₃N / CH₂Cl₂ / 2 h / Heating

5: 100 percent / H₂ / 10percent Pd/C / ethanol / 16 h / Ambient temperature

With hydrogen; potassium carbonate; hydrazine hydrate; triethylamine; palladium on activated charcoal; In ethanol; dichloromethane; dimethyl sulfoxide;
DOI:10.1055/s-1996-4319