1,4-diethyl 2-(3,4-dihydro-6,7-dimethoxy-2H-isoquinoline-1-ylidene)-3-(2-(4-methylphenyl)hydrazono)succinate

Base Information

• Chemical Name: 1,4-diethyl 2-(3,4-dihydro-6,7-dimethoxy-2H-isoquinoline-1-ylidene)-3-(2-(4-methylphenyl)hydrazono)succinate
• CAS No.: 1161946-79-7
• Molecular Formula: C₂₆H₃₁N₃O₆
• Molecular Weight: 481.549
• Mol file: 1161946-79-7.mol

Synonyms:1,4-diethyl 2-(3,4-dihydro-6,7-dimethoxy-2H-isoquinoline-1-ylidene)-3-(2-(4-methylphenyl)hydrazono)succinate

Chemical Property of 1,4-diethyl 2-(3,4-dihydro-6,7-dimethoxy-2H-isoquinoline-1-ylidene)-3-(2-(4-methylphenyl)hydrazono)succinate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,4-diethyl 2-(3,4-dihydro-6,7-dimethoxy-2H-isoquinoline-1-ylidene)-3-(2-(4-methylphenyl)hydrazono)succinate

There total 1 articles about 1,4-diethyl 2-(3,4-dihydro-6,7-dimethoxy-2H-isoquinoline-1-ylidene)-3-(2-(4-methylphenyl)hydrazono)succinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

ethyl 2-chloro-(4-tolylhydrazono)acetate (27171-88-6,132815-69-1) + 1-(ethoxycarbonylmethylene)-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline → 1,4-diethyl 2-(3,4-dihydro-6,7-dimethoxy-2H-isoquinoline-1-ylidene)-3-(2-(4-methylphenyl)hydrazono)succinate (1161946-79-7)

Guidance literature:

With triethylamine; In chloroform; at 20 ℃; for 4h;

DOI:10.3987/COM-09-11648

Reference yield:

1,4-diethyl 2-(3,4-dihydro-6,7-dimethoxy-2H-isoquinoline-1-ylidene)-3-(2-(4-methylphenyl)hydrazono)succinate (1161946-79-7) → ethyl 2,3,5,6-tetrahydro-8,9-dimethoxy-2-(2-(4-methylphenyl)hydrazono)-3-oxopyrrolo[2,1-a]isoquinoline-1-carboxylate (1161946-87-7)

Guidance literature:

With triethylamine; In acetic acid; at 20 ℃; Reflux;

DOI:10.3987/COM-09-11648

upstream raw materials:

ethyl 2-chloro-(4-tolylhydrazono)acetate

Downstream raw materials:

ethyl 2,3,5,6-tetrahydro-8,9-dimethoxy-2-(2-(4-methylphenyl)hydrazono)-3-oxopyrrolo[2,1-a]isoquinoline-1-carboxylate