5'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N⁴-[2-(4-nitrophenyl)ethoxycarbonyl]cytidine

Base Information

• Chemical Name: 5'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N⁴-[2-(4-nitrophenyl)ethoxycarbonyl]cytidine
• CAS No.: 156159-70-5
• Molecular Formula: C₃₃H₃₅N₅O₁₂S
• Molecular Weight: 725.733

Synonyms:5'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N⁴-[2-(4-nitrophenyl)ethoxycarbonyl]cytidine

Chemical Property of 5'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N⁴-[2-(4-nitrophenyl)ethoxycarbonyl]cytidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N⁴-[2-(4-nitrophenyl)ethoxycarbonyl]cytidine

There total 2 articles about 5'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N⁴-[2-(4-nitrophenyl)ethoxycarbonyl]cytidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

2'-deoxy-N4-{[2-(4-nitrophenyl)ethoxy]carbonyl}cytidine (88091-67-2) + (2-{[5-(dimethylamino)naphthalen-1-yl]sulfonyl}ethoxy)carbonyl chloride → 5'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]cytidine (156159-70-5)

Guidance literature:

With pyridine; at 0 ℃;

DOI:10.1080/07328319708006249

Reference yield: 65.0%

2'-deoxy-N4-{[2-(4-nitrophenyl)ethoxy]carbonyl}cytidine (88091-67-2) + 2-dansylethyl chloroformate hydrochloride → bis-(2-dansylethyl)-carbonate + 3'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N4-<2-(4-nitrophenyl)ethoxycarbonyl>cytidine + 5'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]cytidine (156159-70-5) + 3',5'-bis-O-(2-dansylethoxycarbonyl)-2'-deoxy-N4-<2-(4-nitrophenyl)ethoxycarbonyl>cytidine

Guidance literature:

With pyridine; for 1h; Yield given;

DOI:10.1002/hlca.19940770123

Reference yield: 93.0%

4,4'-dimethoxytrityl chloride (40615-36-9) + 5'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N4-[2-(4-nitrophenyl)ethoxycarbonyl]cytidine (156159-70-5) → Carbonic acid (2R,3S,5R)-3-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-5-{4-[2-(4-nitro-phenyl)-ethoxycarbonylamino]-2-oxo-2H-pyrimidin-1-yl}-tetrahydro-furan-2-ylmethyl ester 2-(5-dimethylamino-naphthalene-1-sulfonyl)-ethyl ester (199792-96-6)

Guidance literature:

With pyridine; for 32h; Ambient temperature;

DOI:10.1080/07328319708006249

upstream raw materials:

2'-deoxy-N⁴-{[2-(4-nitrophenyl)ethoxy]carbonyl}cytidine

Downstream raw materials:

5'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N⁴-<2-(4-nitrophenyl)ethoxycarbonyl>-3'-O-succinylcytidine

5'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N⁴-<2-(4-nitrophenyl)ethoxycarbonyl>cytidine 3'-<2-(4-nitrophenyl)ethyl N,N-diethylphosphoramidite>

5'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N⁴-<2-(4-nitrophenyl)ethoxycarbonyl>cytidine 3'-<2-(4-nitrophenyl)ethyl N,N-diisopropylphosphoramidite>

Carbonic acid (2R,3S,5R)-3-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-5-{4-[2-(4-nitro-phenyl)-ethoxycarbonylamino]-2-oxo-2H-pyrimidin-1-yl}-tetrahydro-furan-2-ylmethyl ester 2-(5-dimethylamino-naphthalene-1-sulfonyl)-ethyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 156159-70-5 5'-O-(2-dansylethoxycarbonyl)-2'-deoxy-N⁴-[2-(4-nitrophenyl)ethoxycarbonyl]cytidine

Send

Send

Metric Ton KG G Pound L ML

Send

Send