6-methoxy-2-methyl-1-(4-methylphenyl)sulfonyl-2H-quinoline

Base Information

Chemical Name:6-methoxy-2-methyl-1-(4-methylphenyl)sulfonyl-2H-quinoline
CAS No.:34129-50-5
Molecular Formula:C18H19NO3S
Molecular Weight:329.4134
Hs Code.:
NSC Number:173932
DSSTox Substance ID:DTXSID20306051

Synonyms:34129-50-5;6-methoxy-2-methyl-1-(4-methylphenyl)sulfonyl-2H-quinoline;NSC173932;DTXSID20306051;NSC-173932;Quinoline,2-dihydro-6-methoxy-2-methyl-1-[(4-methylphenyl)sulfonyl]-

Suppliers and Price of 6-methoxy-2-methyl-1-(4-methylphenyl)sulfonyl-2H-quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 6-methoxy-2-methyl-1-(4-methylphenyl)sulfonyl-2H-quinoline

Chemical Property:

Vapor Pressure:4.45E-10mmHg at 25°C
Boiling Point:498.7°C at 760 mmHg
Flash Point:255.4°C
Density:1.228g/cm³
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:329.10856464
Heavy Atom Count:23
Complexity:531

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C=CC2=C(N1S(=O)(=O)C3=CC=C(C=C3)C)C=CC(=C2)OC

Technology Process of 6-methoxy-2-methyl-1-(4-methylphenyl)sulfonyl-2H-quinoline

There total 4 articles about 6-methoxy-2-methyl-1-(4-methylphenyl)sulfonyl-2H-quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

: 1316312-12-5
N-(2-buta-1,3-dienyl-4-methoxy-phenyl)-4-methyl-benzenesulfonamide

: 34129-50-5
6-methoxy-2-methyl-1-(toluene-4-sulfonyl)-1,2-dihydro-quinoline

Guidance literature:: With chlorotriphenylphosphinegold(I); silver trifluoromethanesulfonate; In toluene; at 100 ℃; Inert atmosphere;
DOI:10.1002/ejoc.201100040

Reference yield:

: 1118507-42-8
C₂₀H₂₃NO₃S

: 34129-50-5
6-methoxy-2-methyl-1-(toluene-4-sulfonyl)-1,2-dihydro-quinoline

Guidance literature:: Multi-step reaction with 3 steps

1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 5 h / 20 °C / Inert atmosphere

2: potassium tert-butylate / dimethyl sulfoxide / 0 - 25 °C

3: chlorotriphenylphosphinegold(I); silver trifluoromethanesulfonate / toluene / 100 °C / Inert atmosphere

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; chlorotriphenylphosphinegold(I); potassium tert-butylate; silver trifluoromethanesulfonate; In dichloromethane; dimethyl sulfoxide; toluene;
DOI:10.1002/ejoc.201100040

Reference yield:

: 1118507-59-7
C₁₈H₁₉NO₃S

: 34129-50-5
6-methoxy-2-methyl-1-(toluene-4-sulfonyl)-1,2-dihydro-quinoline

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / dimethyl sulfoxide / 0 - 25 °C

2: chlorotriphenylphosphinegold(I); silver trifluoromethanesulfonate / toluene / 100 °C / Inert atmosphere

With chlorotriphenylphosphinegold(I); potassium tert-butylate; silver trifluoromethanesulfonate; In dimethyl sulfoxide; toluene;
DOI:10.1002/ejoc.201100040