(-)-ethyl-5-{2-[2-(ethoxycarbonyl)ethyl]-3-(7R-hydroxy-5E-pentadecenyloxy)phenoxy}petanoate

Base Information

Chemical Name:(-)-ethyl-5-{2-[2-(ethoxycarbonyl)ethyl]-3-(7R-hydroxy-5E-pentadecenyloxy)phenoxy}petanoate
CAS No.:197726-66-2
Molecular Formula:C₃₃H₅₄O₇
Molecular Weight:562.788
Hs Code.:

Synonyms:(-)-ethyl-5-{2-[2-(ethoxycarbonyl)ethyl]-3-(7R-hydroxy-5E-pentadecenyloxy)phenoxy}petanoate

Suppliers and Price of (-)-ethyl-5-{2-[2-(ethoxycarbonyl)ethyl]-3-(7R-hydroxy-5E-pentadecenyloxy)phenoxy}petanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (-)-ethyl-5-{2-[2-(ethoxycarbonyl)ethyl]-3-(7R-hydroxy-5E-pentadecenyloxy)phenoxy}petanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (-)-ethyl-5-{2-[2-(ethoxycarbonyl)ethyl]-3-(7R-hydroxy-5E-pentadecenyloxy)phenoxy}petanoate

There total 7 articles about (-)-ethyl-5-{2-[2-(ethoxycarbonyl)ethyl]-3-(7R-hydroxy-5E-pentadecenyloxy)phenoxy}petanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 197726-64-0
ethyl-5-{2-[2-(ethoxycarbonyl)ethyl]-3-(7-oxo-5E-pentadecenyloxy)phenoxy}pentanoate

: 197726-66-2
(-)-ethyl-5-{2-[2-(ethoxycarbonyl)ethyl]-3-(7R-hydroxy-5E-pentadecenyloxy)phenoxy}petanoate

: 197726-67-3
(+)-ethyl-5-{2-[2-(ethoxycarbonyl)ethyl]-3-(7S-hydroxy-5E-pentadecenyloxy)phenoxy}petanoate

Guidance literature:: With dimethylsulfide borane complex; boron-methylated (S)-oxazaborolidine reagent; In tetrahydrofuran; at 25 ℃; for 0.0833333h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1016/S0968-0896(97)00090-4

Reference yield:

: 37497-13-5
dimethyl 2-oxodecane-1-phosphonate

: 197726-66-2
(-)-ethyl-5-{2-[2-(ethoxycarbonyl)ethyl]-3-(7R-hydroxy-5E-pentadecenyloxy)phenoxy}petanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) THF, a) 0 deg C, 10 min, b) 25 deg C, 30 min, 2.) THF, 25 deg C, 1 h

2: BH₃-SMe₂, boron-methylated (R)-oxazaborolidine reagent / tetrahydrofuran / 0.08 h / 25 °C

With dimethylsulfide borane complex; boron-methylated (R)-oxazaborolidine reagent; sodium hydride; In tetrahydrofuran;
DOI:10.1016/S0968-0896(97)00090-4

Reference yield:

: 76102-75-5
1-<5-<2-(tetrahydropyranyloxy)>pentyl>methanesulfonate

: 197726-66-2
(-)-ethyl-5-{2-[2-(ethoxycarbonyl)ethyl]-3-(7R-hydroxy-5E-pentadecenyloxy)phenoxy}petanoate

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) NaH / 1.) DMF, a) 0 deg C, 10 min, b) 25 deg C, 30 min, 2.) DMF, 75 deg C, 1 h

2: p-TsOH*H₂O / methanol / 0.5 h / 45 °C

3: 1.) (COCl)2, DMSO, 2.) Et₃N / 1.) CH₂Cl₂, -70 deg C, 30 min, 2.) CH₂Cl₂, 0 deg C, 5 min

4: 1.) NaH / 1.) THF, a) 0 deg C, 10 min, b) 25 deg C, 30 min, 2.) THF, 25 deg C, 1 h

5: BH₃-SMe₂, boron-methylated (R)-oxazaborolidine reagent / tetrahydrofuran / 0.08 h / 25 °C

With oxalyl dichloride; dimethylsulfide borane complex; boron-methylated (R)-oxazaborolidine reagent; sodium hydride; toluene-4-sulfonic acid; dimethyl sulfoxide; triethylamine; In tetrahydrofuran; methanol;
DOI:10.1016/S0968-0896(97)00090-4