2-amino-6-nitrobenzaldehyde ethylene acetal

Base Information

• Chemical Name: 2-amino-6-nitrobenzaldehyde ethylene acetal
• CAS No.: 151585-78-3
• Molecular Formula: C₉H₁₀N₂O₄
• Molecular Weight: 210.189
• Mol file: 151585-78-3.mol

Synonyms:2-amino-6-nitrobenzaldehyde ethylene acetal

Chemical Property of 2-amino-6-nitrobenzaldehyde ethylene acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-amino-6-nitrobenzaldehyde ethylene acetal

There total 2 articles about 2-amino-6-nitrobenzaldehyde ethylene acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2,6-dinitrobenzaldehyde ethylene acetal (151585-77-2) → 2-amino-6-nitrobenzaldehyde ethylene acetal (151585-78-3)

Guidance literature:

With sodium sulfide; In ethanol; water; for 0.5h; Heating;

DOI:10.1021/jm00070a013

Reference yield:

2,6-dinitrobenzaldehyde (606-31-5) → 2-amino-6-nitrobenzaldehyde ethylene acetal (151585-78-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / p-TsOH*H₂O / toluene / 4.5 h / Heating

2: 90 percent / Na₂S*9H₂O / ethanol; H₂O / 0.5 h / Heating

With sodium sulfide; toluene-4-sulfonic acid; In ethanol; water; toluene;

DOI:10.1021/jm00070a013

Reference yield: 89.0%

2-amino-6-nitrobenzaldehyde ethylene acetal (151585-78-3) → 2-amino-6-nitrobenzaldehyde (130133-53-8)

Guidance literature:

With sulfuric acid; In tetrahydrofuran; for 1h;

DOI:10.1021/jm00070a013

upstream raw materials:

2,6-dinitrobenzaldehyde ethylene acetal

2,6-dinitrobenzaldehyde

Downstream raw materials:

2-amino-6-nitrobenzaldehyde

9-amino-20(S)-camptothecin

10-hydroxycamptothecin

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