2-((2,6-difluorophenyl)amino)-2-oxoacetic acid

Base Information

Chemical Name:2-((2,6-difluorophenyl)amino)-2-oxoacetic acid
CAS No.:1018295-42-5
Molecular Formula:C₈H₅F₂NO₃
Molecular Weight:201.129
Hs Code.:
Mol file:1018295-42-5.mol

Synonyms:2-((2,6-difluorophenyl)amino)-2-oxoacetic acid

Suppliers and Price of 2-((2,6-difluorophenyl)amino)-2-oxoacetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-((2,6-Difluorophenyl)amino)-2-oxoaceticAcid
500mg
$ 310.00

Sigma-Aldrich
2,6-Difluoroanilino(oxo)acetic acid
1g
$ 129.00

Sigma-Aldrich
2,6-Difluoroanilino(oxo)acetic acid
250mg
$ 33.00

AK Scientific
2-((2,6-Difluorophenyl)amino)-2-oxoaceticacid
250mg
$ 216.00

AK Scientific
2-((2,6-Difluorophenyl)amino)-2-oxoaceticacid
100mg
$ 201.00

Total 14 raw suppliers

Chemical Property of 2-((2,6-difluorophenyl)amino)-2-oxoacetic acid

Chemical Property:

PKA:2.73±0.40(Predicted)
Density:1.601±0.06 g/cm3(Predicted)

Purity/Quality:

99%, ^*data from raw suppliers

2-((2,6-Difluorophenyl)amino)-2-oxoaceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-((2,6-difluorophenyl)amino)-2-oxoacetic acid

There total 3 articles about 2-((2,6-difluorophenyl)amino)-2-oxoacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 648408-62-2
ethyl 2-((2,6-difluorophenyl)amino)-2-oxoacetate

: 1018295-42-5
2-((2,6-difluorophenyl)amino)-2-oxoacetic acid

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; at 20 ℃; for 4h;

Reference yield:

: 98500-60-8
N-(2,6-difluoro-phenyl)-oxalamic acid methyl ester

: 1018295-42-5
2-((2,6-difluorophenyl)amino)-2-oxoacetic acid

Guidance literature:: With lithium hydroxide; In 1,4-dioxane; at 20 ℃;
DOI:10.1016/j.bmcl.2003.12.106

Reference yield:

: 5509-65-9
2,6-difluoroaniline

: 1018295-42-5
2-((2,6-difluorophenyl)amino)-2-oxoacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / 0 - 20 °C

2: aq. LiOH / dioxane / 20 °C

With lithium hydroxide; triethylamine; In 1,4-dioxane;
DOI:10.1016/j.bmcl.2003.12.106