Technology Process of C16H15(2)H4F5O3
There total 7 articles about C16H15(2)H4F5O3 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
deuterium;
platinum on activated charcoal;
In
deuteromethanol;
for 5h;
under 672.3 Torr;
Ambient temperature;
DOI:10.1080/00397919508015474
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 1.) n-BuLi / 1.) THF, HMPA, RT, 30 min, 2.) THF, RT, 24 h
2: 100 percent Chromat. / 5percent aq. HCl / tetrahydrofuran / 8 h / Heating
3: 3.7 g / dimethylsulfoxide / 13 h / Heating
4: 65 percent / 25percent aq. KOH / tetrahydrofuran
5: 1.) NaHCO3 / 1.) DME, reflux, 2 h, 2.) DME, reflux, 36 h
6: 91 percent Chromat. / D2 / 5percent Pt/C / CH3OD / 5 h / 672.3 Torr / Ambient temperature
With
hydrogenchloride; potassium hydroxide; n-butyllithium; sodium hydrogencarbonate; deuterium;
platinum on activated charcoal;
In
tetrahydrofuran; deuteromethanol; dimethyl sulfoxide;
DOI:10.1080/00397919508015474
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 100 percent / conc. HCl / CH2Cl2 / Ambient temperature
2: 1.) n-BuLi / 1.) THF, HMPA, RT, 30 min, 2.) THF, RT, 24 h
3: 100 percent Chromat. / 5percent aq. HCl / tetrahydrofuran / 8 h / Heating
4: 3.7 g / dimethylsulfoxide / 13 h / Heating
5: 65 percent / 25percent aq. KOH / tetrahydrofuran
6: 1.) NaHCO3 / 1.) DME, reflux, 2 h, 2.) DME, reflux, 36 h
7: 91 percent Chromat. / D2 / 5percent Pt/C / CH3OD / 5 h / 672.3 Torr / Ambient temperature
With
hydrogenchloride; potassium hydroxide; n-butyllithium; sodium hydrogencarbonate; deuterium;
platinum on activated charcoal;
In
tetrahydrofuran; dichloromethane; deuteromethanol; dimethyl sulfoxide;
DOI:10.1080/00397919508015474
