1-(4-amino-3-methylphenyl)-1-(4-bromodifluoromethoxyphenyl)-2,2,2-trifluoroethanol

Base Information

Chemical Name:1-(4-amino-3-methylphenyl)-1-(4-bromodifluoromethoxyphenyl)-2,2,2-trifluoroethanol
CAS No.:849370-47-4
Molecular Formula:C₁₆H₁₃BrF₅NO₂
Molecular Weight:426.181
Hs Code.:

Synonyms:1-(4-amino-3-methylphenyl)-1-(4-bromodifluoromethoxyphenyl)-2,2,2-trifluoroethanol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(4-amino-3-methylphenyl)-1-(4-bromodifluoromethoxyphenyl)-2,2,2-trifluoroethanol

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Technology Process of 1-(4-amino-3-methylphenyl)-1-(4-bromodifluoromethoxyphenyl)-2,2,2-trifluoroethanol

There total 1 articles about 1-(4-amino-3-methylphenyl)-1-(4-bromodifluoromethoxyphenyl)-2,2,2-trifluoroethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 849370-46-3
t-butyl 4-[1-(4-bromodifluoromethoxyphenyl)-2,2,2-trifluoro-1-hydroxyethyl]-2-methylcarbanilate

: 849370-47-4
1-(4-amino-3-methylphenyl)-1-(4-bromodifluoromethoxyphenyl)-2,2,2-trifluoroethanol

Guidance literature:: t-butyl 4-[1-(4-bromodifluoromethoxyphenyl)-2,2,2-trifluoro-1-hydroxyethyl]-2-methylcarbanilate; With trifluoroacetic acid; at 0 - 20 ℃; for 0.333333h;

With potassium carbonate; In water; at 0 ℃;

Reference yield:

: 226979-91-5
3-iodo-N-isopropylphthalamidic acid

: 849370-47-4
1-(4-amino-3-methylphenyl)-1-(4-bromodifluoromethoxyphenyl)-2,2,2-trifluoroethanol

: N₁-[4-[1-(4-bromodifluoromethoxyphenyl)-2,2,2-trifluoro-1-hydroxyethyl]-2-methylphenyl]-3-iodo-N₂-isopropylphthalic diamide

Guidance literature:: 3-iodo-N-isopropylphthalamidic acid; With trifluoroacetic anhydride; In toluene; at 20 ℃; for 1h;

1-(4-amino-3-methylphenyl)-1-(4-bromodifluoromethoxyphenyl)-2,2,2-trifluoroethanol; In acetonitrile; at 20 ℃; for 15h;