Chemical Property of Adipic dihydrazide
Chemical Property:
- Appearance/Colour:white to slightly yellow crystalline powder
- Vapor Pressure:6.92E-11mmHg at 25°C
- Melting Point:175-182 °C
- Refractive Index:1.513
- Boiling Point:519.3 °C at 760 mmHg
- PKA:12.93±0.35(Predicted)
- Flash Point:267.9 °C
- PSA：110.24000
- Density:1.186 g/cm3
- LogP:0.70900
- Storage Temp.:−20°C
- Solubility.:H2O: 100 mg/mL
- Water Solubility.:soluble
- XLogP3:-2.1
- Hydrogen Bond Donor Count:4
- Hydrogen Bond Acceptor Count:4
- Rotatable Bond Count:5
- Exact Mass:174.11167570
- Heavy Atom Count:12
- Complexity:142
- Purity/Quality:
-
99% *data from raw suppliers
Adipic dihydrazide *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xi
- Hazard Codes:Xi
- Statements:
36/37/38
- Safety Statements:
22-24/25
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C(CCC(=O)NN)CC(=O)NN
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Description
Adipic dihydrazide (ADH) is the most suitable hydrazide cross-linking agent, and ADH has been widely used in water-based paint emulsions in combination with diacetone acrylamide. ADH is weakly alkaline, and there is a possibility of agglomeration when solid ADH is added directly to the emulsion, so usually ADH should be dissolved in hot water before use.
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Uses
Adipic dihydrazide is used as a formaldehyde scavenger and reacts with formaldehyde, thereby preventing the volatilizing of formaldehyde in the air. It is also employed as a paint additive and coating additive. It is also used as an intermediate. Further, it is used for cross-linking water-based emulsions and as a hardener for certain epoxy resins, which finds application in powder coating. Adipic acid dihydrazide is a homobifunctional cross-linking reagent specific for aldehydes resulting in relatively stable hydrazone linkages. Adipic acid dihydrazide is typically, used in the linking of glycoproteins, such as antibodies, in a site specific fashion following periodate oxidation. Oxidation and coupling may conveniently be performed at pH 5.0 due to the low pKa of the hydrazide which avoids competition by primary amines.
