C₂₀H₂₂O₆

Base Information

• Chemical Name: C₂₀H₂₂O₆
• CAS No.: 1312943-79-5
• Molecular Formula: C₂₀H₂₂O₆
• Molecular Weight: 358.391
• Mol file: 1312943-79-5.mol

Synonyms:C₂₀H₂₂O₆

Chemical Property of C₂₀H₂₂O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₀H₂₂O₆

There total 7 articles about C₂₀H₂₂O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

benzo[1,3]dioxol-5-ylbromoacetic acid ethyl ester (91065-93-9) + 2-(3-methoxyphenyl)acetaldehyde (65292-99-1) → C20H22O6 (1312943-79-5)

Guidance literature:

benzo[1,3]dioxol-5-ylbromoacetic acid ethyl ester; With chloro-trimethyl-silane; ethylene dibromide; zinc; In tetrahydrofuran; at 20 ℃; for 0.5h;

2-(3-methoxyphenyl)acetaldehyde; In tetrahydrofuran; at 20 ℃; for 2h; Reflux;

DOI:10.1016/j.tetlet.2011.04.069

Reference yield:

benzo[1,3]dioxol-5-ylhydroxyacetic acid ethyl ester (115124-42-0) → C20H22O6 (1312943-79-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: phosphorus tribromide / dichloromethane / 0 °C

2.1: chloro-trimethyl-silane; ethylene dibromide; zinc / tetrahydrofuran / 0.5 h / 20 °C

2.2: 2 h / 20 °C / Reflux

With chloro-trimethyl-silane; phosphorus tribromide; ethylene dibromide; zinc; In tetrahydrofuran; dichloromethane; 2.1: Reformatsky reaction / 2.2: Reformatsky reaction;

DOI:10.1016/j.tetlet.2011.04.069

Reference yield:

Na-3-(3-methoxy-phenyl)-glycidat (68432-82-6) → C20H22O6 (1312943-79-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: hydrogenchloride; sodium dihydrogenphosphate / water / 20 °C

2.1: chloro-trimethyl-silane; ethylene dibromide; zinc / tetrahydrofuran / 0.5 h / 20 °C

2.2: 2 h / 20 °C / Reflux

With hydrogenchloride; sodium dihydrogenphosphate; chloro-trimethyl-silane; ethylene dibromide; zinc; In tetrahydrofuran; water; 2.1: Reformatsky reaction / 2.2: Reformatsky reaction;

DOI:10.1016/j.tetlet.2011.04.069

upstream raw materials:

Methylenedioxybenzene

ethyl β-(m-methoxy)phenylglycidate

benzo[1,3]dioxol-5-ylbromoacetic acid ethyl ester

2-(3-methoxyphenyl)acetaldehyde