2-(3-bromophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole

Base Information

Chemical Name:2-(3-bromophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole
CAS No.:1391615-32-9
Molecular Formula:C₁₃H₁₀BrN₅O₃
Molecular Weight:364.158
Hs Code.:

Synonyms:2-(3-bromophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole

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Chemical Property of 2-(3-bromophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole

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Technology Process of 2-(3-bromophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole

There total 2 articles about 2-(3-bromophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 126359-46-4
2-(2-methyl-5-nitro-1H-imidazol-1-yl)acetohydrazide

: 585-76-2
m-bromobenzoic acid

: 1391615-32-9
2-(3-bromophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole

Guidance literature:: 2-(2-methyl-5-nitro-1H-imidazol-1-yl)acetohydrazide; m-bromobenzoic acid; With trichlorophosphate; Reflux;

With sodium hydrogencarbonate; In water;
DOI:10.1016/j.bmc.2012.05.050

Reference yield:

: 1016-40-6
ethyl 2-(2-methyl-5-nitro-1H-imidazole-1-yl)acetate

: 1391615-32-9
2-(3-bromophenyl)-5-((2-methyl-5-nitro-1H-imidazol-1-yl)methyl)-1,3,4-oxadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine hydrate / methanol / 4.5 h / 0 °C / Inert atmosphere

2: trichlorophosphate / Reflux

With hydrazine hydrate; trichlorophosphate; In methanol;
DOI:10.1016/j.bmc.2012.05.050