(+/-)-cis/trans-2-[2-(tert-butyldiphenylsiloxy)ethyl]-2,3,5,6-tetrahydro-4H-pyran-3-ol

Base Information

• Chemical Name: (+/-)-cis/trans-2-[2-(tert-butyldiphenylsiloxy)ethyl]-2,3,5,6-tetrahydro-4H-pyran-3-ol
• CAS No.: 1222446-72-1
• Molecular Formula: C₂₃H₃₂O₃Si
• Molecular Weight: 384.591
• Mol file: 1222446-72-1.mol

Synonyms:(+/-)-cis/trans-2-[2-(tert-butyldiphenylsiloxy)ethyl]-2,3,5,6-tetrahydro-4H-pyran-3-ol

Chemical Property of (+/-)-cis/trans-2-[2-(tert-butyldiphenylsiloxy)ethyl]-2,3,5,6-tetrahydro-4H-pyran-3-ol

Chemical Property:

Purity/Quality:

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Technology Process of (+/-)-cis/trans-2-[2-(tert-butyldiphenylsiloxy)ethyl]-2,3,5,6-tetrahydro-4H-pyran-3-ol

There total 1 articles about (+/-)-cis/trans-2-[2-(tert-butyldiphenylsiloxy)ethyl]-2,3,5,6-tetrahydro-4H-pyran-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

C7H14O3 (738604-56-3) + tert-butylchlorodiphenylsilane (58479-61-1) → (+/-)-cis/trans-2-[2-(tert-butyldiphenylsiloxy)ethyl]-2,3,5,6-tetrahydro-4H-pyran-3-ol (1222446-72-1)

Guidance literature:

With 1H-imidazole; dmap; In N,N-dimethyl-formamide; at 20 ℃; for 1h;

DOI:10.1055/s-0029-1217142

Reference yield: 97.0%

(+/-)-cis/trans-2-[2-(tert-butyldiphenylsiloxy)ethyl]-2,3,5,6-tetrahydro-4H-pyran-3-ol (1222446-72-1) → (+/-)-2-[2-(tert-Butyldiphenylsiloxy)ethyl]-2,3,5,6-tetrahydro-4H-pyran-3-one (1222446-74-3)

Guidance literature:

With tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide; In dichloromethane; for 0.666667h; Molecular sieve;

DOI:10.1055/s-0029-1217142

upstream raw materials:

C₇H₁₄O₃

tert-butylchlorodiphenylsilane

Downstream raw materials:

(+/-)-2-[2-(tert-Butyldiphenylsiloxy)ethyl]-2,3,5,6-tetrahydro-4H-pyran-3-one