methyl 5-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)acetyl)-2-(pentyloxy)benzoate

Base Information

Chemical Name:methyl 5-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)acetyl)-2-(pentyloxy)benzoate
CAS No.:1373428-05-7
Molecular Formula:C₂₉H₄₀N₂O₇
Molecular Weight:528.646
Hs Code.:

Synonyms:methyl 5-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)acetyl)-2-(pentyloxy)benzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 5-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)acetyl)-2-(pentyloxy)benzoate

Chemical Property:

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Technology Process of methyl 5-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)acetyl)-2-(pentyloxy)benzoate

There total 9 articles about methyl 5-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)acetyl)-2-(pentyloxy)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.9%

: 1373427-96-3
methyl 5-(2-bromoacetyl)-2-pentyloxybenzoate

: 5011-34-7
1-(2,3,4-trimethoxybenzyl)piperazine

: 1373428-05-7
methyl 5-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)acetyl)-2-(pentyloxy)benzoate

Guidance literature:: With potassium carbonate; In acetonitrile; at 20 ℃;
DOI:10.1002/cjoc.201180470

Reference yield:

: 500869-36-3
C₁₇H₁₄O₅

: 1373428-05-7
methyl 5-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)acetyl)-2-(pentyloxy)benzoate

Guidance literature:: Multi-step reaction with 5 steps

1: bromine / chloroform / 20 °C

2: potassium carbonate / acetonitrile / 20 °C

3: potassium carbonate / methanol / 50 °C

4: thionyl chloride

5: potassium carbonate / acetonitrile / Reflux

With thionyl chloride; bromine; potassium carbonate; In methanol; chloroform; acetonitrile;
DOI:10.1002/cjoc.201180470

Reference yield:

: 1373428-27-3
C₂₃H₂₈N₂O₇

: 1373428-05-7
methyl 5-(2-(4-(2,3,4-trimethoxybenzyl)piperazin-1-yl)acetyl)-2-(pentyloxy)benzoate

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride

2: potassium carbonate / acetonitrile / Reflux

With thionyl chloride; potassium carbonate; In acetonitrile;
DOI:10.1002/cjoc.201180470