N-(benzyloxycarbonyl)-γ-L-glutamyl-L-glutamic acid, α,α'-di-tert-butyl γ-methyl triester

Base Information Edit

Chemical Name:N-(benzyloxycarbonyl)-γ-L-glutamyl-L-glutamic acid, α,α'-di-tert-butyl γ-methyl triester
CAS No.:23736-78-9
Molecular Formula:C₂₇H₄₀N₂O₉
Molecular Weight:536.623
Hs Code.:
Mol file:23736-78-9.mol

Synonyms:N-(benzyloxycarbonyl)-γ-L-glutamyl-L-glutamic acid, α,α'-di-tert-butyl γ-methyl triester

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Chemical Property of N-(benzyloxycarbonyl)-γ-L-glutamyl-L-glutamic acid, α,α'-di-tert-butyl γ-methyl triester Edit

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Technology Process of N-(benzyloxycarbonyl)-γ-L-glutamyl-L-glutamic acid, α,α'-di-tert-butyl γ-methyl triester

There total 5 articles about N-(benzyloxycarbonyl)-γ-L-glutamyl-L-glutamic acid, α,α'-di-tert-butyl γ-methyl triester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.3%

: 25456-73-9
Z-Glu(OPcp)-OBu^t

: 34582-33-7
α-tert-butyl-γ-methyl L-Glu diester hydrochloride

: 23736-78-9
N-(benzyloxycarbonyl)-γ-L-glutamyl-L-glutamic acid, α,α'-di-tert-butyl γ-methyl triester

Guidance literature:

Reference yield:

: 57732-63-5
1-tert-butyl 5-methyl (2S)-2-{[(benzyloxy)carbonyl]amino}pentanedioate

: 23736-78-9
N-(benzyloxycarbonyl)-γ-L-glutamyl-L-glutamic acid, α,α'-di-tert-butyl γ-methyl triester

Guidance literature:: Multi-step reaction with 2 steps

1: NaOH

2: dicyclohexylcarbodiimide (DCC) / CH₂Cl₂

With sodium hydroxide; dicyclohexyl-carbodiimide; In dichloromethane;
DOI:10.1021/ja00068a022