(1R,4S,5S,6S,8S)-1-methyl-4-isopropenyl-5-<(4'-methoxybenzyloxy)methoxymethyl>-6,8-dihydroxy-9-methylene-cis-bicyclo<4.3.0^1,6>non-2-ene

Base Information

• Chemical Name: (1R,4S,5S,6S,8S)-1-methyl-4-isopropenyl-5-<(4'-methoxybenzyloxy)methoxymethyl>-6,8-dihydroxy-9-methylene-cis-bicyclo<4.3.0^1,6>non-2-ene
• CAS No.: 244170-93-2
• Molecular Formula: C₂₄H₃₂O₅
• Molecular Weight: 400.515

Synonyms:(1R,4S,5S,6S,8S)-1-methyl-4-isopropenyl-5-<(4'-methoxybenzyloxy)methoxymethyl>-6,8-dihydroxy-9-methylene-cis-bicyclo<4.3.0^1,6>non-2-ene

Chemical Property of (1R,4S,5S,6S,8S)-1-methyl-4-isopropenyl-5-<(4'-methoxybenzyloxy)methoxymethyl>-6,8-dihydroxy-9-methylene-cis-bicyclo<4.3.0^1,6>non-2-ene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (1R,4S,5S,6S,8S)-1-methyl-4-isopropenyl-5-<(4'-methoxybenzyloxy)methoxymethyl>-6,8-dihydroxy-9-methylene-cis-bicyclo<4.3.0^1,6>non-2-ene

There total 4 articles about (1R,4S,5S,6S,8S)-1-methyl-4-isopropenyl-5-<(4'-methoxybenzyloxy)methoxymethyl>-6,8-dihydroxy-9-methylene-cis-bicyclo<4.3.0^1,6>non-2-ene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(4R,5R,6S,2'RS)-1-methyl-4-isopropenyl-5-(4''-methoxybenzyloxy)methoxymethyl-6-(2'-hydroxybut-3'-yn-1'-yl)-6-hydroxycyclohex-1-ene → (1R,4S,5S,6S,8S)-1-methyl-4-isopropenyl-5-<(4'-methoxybenzyloxy)methoxymethyl>-6,8-dihydroxy-9-methylene-cis-bicyclo<4.3.01,6>non-2-ene (244170-93-2)

Guidance literature:

Multi-step reaction with 4 steps

1: imidazole / dimethylformamide / 2.5 h / 60 °C

2: hexamethyldisilazane, pyridine / dimethylformamide / 6.5 h / Ambient temperature

3: Pd(OAc)2, N,N-bis(phenylmethylene)-1,2-ethylene diamine / 1,2-dichloro-ethane / 23 h / 56 °C

4: KF*2H₂O, n-Bu₄NCl / acetonitrile / 24 h / Heating

With pyridine; 1H-imidazole; palladium diacetate; potassium fluoride; N,N'-bis(benzyliden)ethylendiamine; tetrabutyl-ammonium chloride; 1,1,1,3,3,3-hexamethyl-disilazane; In 1,2-dichloro-ethane; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

(1R,5R,6R)-1-[2-(tert-Butyl-dimethyl-silanyloxy)-but-3-ynyl]-5-isopropenyl-6-(4-methoxy-benzyloxymethoxymethyl)-2-methyl-cyclohex-2-enol → (1R,4S,5S,6S,8S)-1-methyl-4-isopropenyl-5-<(4'-methoxybenzyloxy)methoxymethyl>-6,8-dihydroxy-9-methylene-cis-bicyclo<4.3.01,6>non-2-ene (244170-93-2)

Guidance literature:

Multi-step reaction with 3 steps

1: hexamethyldisilazane, pyridine / dimethylformamide / 6.5 h / Ambient temperature

2: Pd(OAc)2, N,N-bis(phenylmethylene)-1,2-ethylene diamine / 1,2-dichloro-ethane / 23 h / 56 °C

3: KF*2H₂O, n-Bu₄NCl / acetonitrile / 24 h / Heating

With pyridine; palladium diacetate; potassium fluoride; N,N'-bis(benzyliden)ethylendiamine; tetrabutyl-ammonium chloride; 1,1,1,3,3,3-hexamethyl-disilazane; In 1,2-dichloro-ethane; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

(4R,5R,6S,1'RS)-1-methyl-4-isopropenyl-5-<(4''-methoxybenzyloxy)methoxymethyl>-6-(1'-tert-butyldimethylsilyloxyprop-3'-ynyl)methyl-6-trimethylsilyloxycyclohex-1-ene (244170-92-1) → (1R,4S,5S,6S,8S)-1-methyl-4-isopropenyl-5-<(4'-methoxybenzyloxy)methoxymethyl>-6,8-dihydroxy-9-methylene-cis-bicyclo<4.3.01,6>non-2-ene (244170-93-2)

Guidance literature:

Multi-step reaction with 2 steps

1: Pd(OAc)2, N,N-bis(phenylmethylene)-1,2-ethylene diamine / 1,2-dichloro-ethane / 23 h / 56 °C

2: KF*2H₂O, n-Bu₄NCl / acetonitrile / 24 h / Heating

With palladium diacetate; potassium fluoride; N,N'-bis(benzyliden)ethylendiamine; tetrabutyl-ammonium chloride; In 1,2-dichloro-ethane; acetonitrile;

upstream raw materials:

(4R,5R,6S,1'RS)-1-methyl-4-isopropenyl-5-<(4''-methoxybenzyloxy)methoxymethyl>-6-(1'-tert-butyldimethylsilyloxyprop-3'-ynyl)methyl-6-trimethylsilyloxycyclohex-1-ene

Downstream raw materials:

(3aR,3bR,6R,7R,7aR,8aR)-3a-Benzyloxymethyl-6-isopropenyl-7-(4-methoxy-benzyloxymethoxymethyl)-2,2,3b-trimethyl-3a,3b,6,7,8,8a-hexahydro-indeno[1,2-d][1,3]dioxol-7a-ol

(1R,2R,3aR,4R,5R,7aR)-1-Benzyloxymethyl-5-isopropenyl-4-(4-methoxy-benzyloxymethoxymethyl)-7a-methyl-1,2,3,4,5,7a-hexahydro-indene-1,2,3a-triol

(3aR,3bR,6R,7S,7aR,8aR)-3a-Benzyloxymethyl-7a-hydroxy-6-isopropenyl-2,2,3b-trimethyl-3b,6,7,7a,8,8a-hexahydro-3aH-indeno[1,2-d][1,3]dioxole-7-carboxylic acid

(3aR,3bR,6R,7R,7aR,8aR)-3a-Benzyloxymethyl-7-hydroxymethyl-6-isopropenyl-2,2,3b-trimethyl-3a,3b,6,7,8,8a-hexahydro-indeno[1,2-d][1,3]dioxol-7a-ol

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 244170-93-2 (1R,4S,5S,6S,8S)-1-methyl-4-isopropenyl-5-<(4'-methoxybenzyloxy)methoxymethyl>-6,8-dihydroxy-9-methylene-cis-bicyclo<4.3.0^1,6>non-2-ene

Send

Send

Metric Ton KG G Pound L ML

Send

Send