phenylmethyl (2S)-2-amino-4-(7-methoxy-2-phenyl(4-quinolyloxy))butanoate hydrochloride

Base Information

Chemical Name:phenylmethyl (2S)-2-amino-4-(7-methoxy-2-phenyl(4-quinolyloxy))butanoate hydrochloride
CAS No.:918650-48-3
Molecular Formula:C₂₇H₂₆N₂O₄*ClH
Molecular Weight:478.975
Hs Code.:

Synonyms:phenylmethyl (2S)-2-amino-4-(7-methoxy-2-phenyl(4-quinolyloxy))butanoate hydrochloride

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Chemical Property of phenylmethyl (2S)-2-amino-4-(7-methoxy-2-phenyl(4-quinolyloxy))butanoate hydrochloride

Chemical Property:

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Technology Process of phenylmethyl (2S)-2-amino-4-(7-methoxy-2-phenyl(4-quinolyloxy))butanoate hydrochloride

There total 3 articles about phenylmethyl (2S)-2-amino-4-(7-methoxy-2-phenyl(4-quinolyloxy))butanoate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1108656-97-8
C₃₂H₃₄N₂O₆

: 918650-48-3
phenylmethyl (2S)-2-amino-4-(7-methoxy-2-phenyl(4-quinolyloxy))butanoate hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; for 120h;

Reference yield:

: 105183-60-6
(S)-benzyl 2-((tert-butoxycarbonyl)amino)-4-hydroxybutanoate

: 918650-48-3
phenylmethyl (2S)-2-amino-4-(7-methoxy-2-phenyl(4-quinolyloxy))butanoate hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 0 - 20 °C

2: hydrogenchloride / 1,4-dioxane / 20 °C

With hydrogenchloride; di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1016/j.bmcl.2015.07.020

Reference yield:

: 20430-72-2,189816-04-4
7-methoxy-2-phenylquinolin-4-ol

: 918650-48-3
phenylmethyl (2S)-2-amino-4-(7-methoxy-2-phenyl(4-quinolyloxy))butanoate hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: di-isopropyl azodicarboxylate; triphenylphosphine / tetrahydrofuran / 0 - 20 °C

2: hydrogenchloride / 1,4-dioxane / 20 °C

With hydrogenchloride; di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1016/j.bmcl.2015.07.020