Technology Process of C22H24N2
There total 6 articles about C22H24N2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-(5-(4-(t-butyl)phenyl)naphthalen-1-yl)acetonitrile;
With
hydrogenchloride;
In
1,4-dioxane; diethyl ether;
at 0 ℃;
for 4h;
With
ammonium hydroxide;
In
ethanol;
for 6h;
Reflux;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate / tetrakis(triphenylphosphine) palladium(0) / 1,4-dioxane; water / 5 h / 100 °C / Inert atmosphere
2.1: sodium tetrahydroborate / ethanol / 1 h / 20 °C
3.1: triethylamine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere
4.1: dimethyl sulfoxide / 20 °C
5.1: hydrogenchloride / 1,4-dioxane; diethyl ether / 4 h / 0 °C
5.2: 6 h / Reflux
With
hydrogenchloride; sodium tetrahydroborate; potassium carbonate; triethylamine;
tetrakis(triphenylphosphine) palladium(0);
In
1,4-dioxane; diethyl ether; ethanol; dichloromethane; water; dimethyl sulfoxide;
1.1: Suzuki Coupling;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium carbonate / tetrakis(triphenylphosphine) palladium(0) / 1,4-dioxane; water / 5 h / 100 °C / Inert atmosphere
2.1: sodium tetrahydroborate / ethanol / 1 h / 20 °C
3.1: triethylamine / dichloromethane / 0.5 h / 0 °C / Inert atmosphere
4.1: dimethyl sulfoxide / 20 °C
5.1: hydrogenchloride / 1,4-dioxane; diethyl ether / 4 h / 0 °C
5.2: 6 h / Reflux
With
hydrogenchloride; sodium tetrahydroborate; potassium carbonate; triethylamine;
tetrakis(triphenylphosphine) palladium(0);
In
1,4-dioxane; diethyl ether; ethanol; dichloromethane; water; dimethyl sulfoxide;
1.1: Suzuki Coupling;
