C₂₀H₃₃NO₃Si

Base Information

• Chemical Name: C₂₀H₃₃NO₃Si
• CAS No.: 1338066-97-9
• Molecular Formula: C₂₀H₃₃NO₃Si
• Molecular Weight: 363.572
• Mol file: 1338066-97-9.mol

Synonyms:C₂₀H₃₃NO₃Si

Chemical Property of C₂₀H₃₃NO₃Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₂₀H₃₃NO₃Si

There total 1 articles about C₂₀H₃₃NO₃Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-(4-methoxyphenyl)-3,6,6-trimethyl-5,6-dihydro-4H-1,2-oxazine 2-oxide (929878-88-6) + t-butyldimethylsiyl triflate (69739-34-0) → C20H33NO3Si (1338066-97-9)

Guidance literature:

With triethylamine; In dichloromethane; at -78 ℃; for 2h; Inert atmosphere;

DOI:10.1055/s-0030-1260108

Reference yield:

C20H33NO3Si (1338066-97-9) → C20H33NO3Si

Guidance literature:

With tetrabutyl ammonium fluoride; In dichloromethane; at -78 - 20 ℃; for 1.58333h; Molecular sieve; Inert atmosphere;

DOI:10.1055/s-0030-1260108

Reference yield:

C20H33NO3Si (1338066-97-9) → 4-(4-methoxyphenyl)-6,6-dimethyldihydro-2H-pyran-3(4H)-one oxime (1338066-98-0) + 4-(4-methoxyphenyl)-6,6-dimethyldihydro-2H-pyran-3(4H)-one oxime (1338067-11-0)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrabutyl ammonium fluoride / dichloromethane / 1.58 h / -78 - 20 °C / Molecular sieve; Inert atmosphere

2: trifluoroacetic acid / methanol; dichloromethane / 1.3 h

With tetrabutyl ammonium fluoride; trifluoroacetic acid; In methanol; dichloromethane;

DOI:10.1055/s-0030-1260108

upstream raw materials:

4-(4-methoxyphenyl)-3,6,6-trimethyl-5,6-dihydro-4H-1,2-oxazine 2-oxide

t-butyldimethylsiyl triflate

Downstream raw materials:

4-(4-methoxyphenyl)-6,6-dimethyldihydro-2H-pyran-3(4H)-one oxime

4-(4-methoxyphenyl)-6,6-dimethyldihydro-2H-pyran-3(4H)-one oxime