C₂₅H₂₄N₂O₁₁

Base Information

• Chemical Name: C₂₅H₂₄N₂O₁₁
• CAS No.: 915720-02-4
• Molecular Formula: C₂₅H₂₄N₂O₁₁
• Molecular Weight: 528.472
• Mol file: 915720-02-4.mol

Synonyms:C₂₅H₂₄N₂O₁₁

Chemical Property of C₂₅H₂₄N₂O₁₁

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₅H₂₄N₂O₁₁

There total 6 articles about C₂₅H₂₄N₂O₁₁ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

C16H18N2O8 (915720-00-2) + 4-acetyloxy-benzoic acid (2345-34-8) → C25H24N2O11 (915720-02-4)

Guidance literature:

With triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran;

DOI:10.1016/j.tetlet.2006.08.119

Reference yield:

1H-pyrrole-2-carboxylic acid 4,5-diacetoxy-6-acetoxymethyl-2-hydroxy-tetrahydro-pyran-3-yl ester → C25H24N2O11 (915720-02-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 81 percent / DBU / CH₂Cl₂ / 0 °C

2: 89 percent / BF₃-OEt₂ / CH₂Cl₂ / 0 °C

3: 86 percent / Candida antarctica lipase; NH₄OAc / acetonitrile / 40 °C

4: 75 percent / PPh₃; DEAD / tetrahydrofuran

With Candida antarctica lipase; boron trifluoride diethyl etherate; ammonium acetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane; acetonitrile; 4: Mitsunobu reaction;

DOI:10.1016/j.tetlet.2006.08.119

Reference yield:

1H-pyrrole-2-carboxylic acid 2,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-3-yl ester (915719-96-9) → C25H24N2O11 (915720-02-4)

Guidance literature:

Multi-step reaction with 5 steps

1: 73 percent / hydrazine acetate / dimethylformamide

2: 81 percent / DBU / CH₂Cl₂ / 0 °C

3: 89 percent / BF₃-OEt₂ / CH₂Cl₂ / 0 °C

4: 86 percent / Candida antarctica lipase; NH₄OAc / acetonitrile / 40 °C

5: 75 percent / PPh₃; DEAD / tetrahydrofuran

With Candida antarctica lipase; boron trifluoride diethyl etherate; ammonium acetate; hydrazinium monoacetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; acetonitrile; 5: Mitsunobu reaction;

DOI:10.1016/j.tetlet.2006.08.119

upstream raw materials:

C₁₆H₁₈N₂O₈

4-acetyloxy-benzoic acid

1H-pyrrole-2-carboxylic acid 2,4,5-triacetoxy-6-acetoxymethyl-tetrahydro-pyran-3-yl ester

C₂₂H₂₄N₂O₁₁