bromo(3-bromophenyl)acetonitrile

Base Information

• Chemical Name: bromo(3-bromophenyl)acetonitrile
• CAS No.: 1052175-54-8
• Molecular Formula: C₈H₅Br₂N
• Molecular Weight: 274.942
• Mol file: 1052175-54-8.mol

Synonyms:bromo(3-bromophenyl)acetonitrile

Chemical Property of bromo(3-bromophenyl)acetonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of bromo(3-bromophenyl)acetonitrile

There total 1 articles about bromo(3-bromophenyl)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(3-bromophenyl)acetonitrile (31938-07-5) → bromo(3-bromophenyl)acetonitrile (1052175-54-8)

Guidance literature:

With bromine; In benzene; at 105 - 110 ℃; for 0.25h;

DOI:10.1016/S0014-827X(00)00087-2

Reference yield: 75.0%

bromo(3-bromophenyl)acetonitrile (1052175-54-8) → m-bromobenzoyl cyanide (24999-51-7)

Guidance literature:

With silver nitrate; In acetonitrile; at 50 ℃; for 10h;

DOI:10.1016/j.tetlet.2008.06.034

Reference yield:

bromo(3-bromophenyl)acetonitrile (1052175-54-8) → 2-{2-[(3-bromo-phenyl)-phenyl-methyl]-thiazol-4-yl}-ethylamine

Guidance literature:

Multi-step reaction with 4 steps

1: AlCl₃ / 1 h / Heating

2: 58 percent / H₂S; pyridine; Et₃N / 12 h / 20 °C

3: 60 percent / aq. HCl / propan-1-ol / 2 h / Heating

4: 73 percent / N₂H₄ / methanol / 2.5 h

With pyridine; hydrogenchloride; aluminium trichloride; hydrogen sulfide; triethylamine; hydrazine; In methanol; propan-1-ol;

DOI:10.1016/S0014-827X(00)00087-2

upstream raw materials:

(3-bromophenyl)acetonitrile

Downstream raw materials:

2-(3-bromo-phenyl)-2-phenyl-thioacetamide

2-(2-{2-[(3-bromo-phenyl)-phenyl-methyl]-thiazol-4-yl}-ethyl)-isoindole-1,3-dione

m-bromobenzoyl cyanide