6-(((1-((5-chloro-2-phenyl-benzofuran-7-yl)methyl)-5-methyl-1H-pyrazol-3-yl)carbonyl)amino)-3-pyridinecarboxylic acid

Base Information

• Chemical Name: 6-(((1-((5-chloro-2-phenyl-benzofuran-7-yl)methyl)-5-methyl-1H-pyrazol-3-yl)carbonyl)amino)-3-pyridinecarboxylic acid
• CAS No.: 1048994-08-6
• Molecular Formula: C₂₆H₁₉ClN₄O₄
• Molecular Weight: 486.914

Synonyms:6-(((1-((5-chloro-2-phenyl-benzofuran-7-yl)methyl)-5-methyl-1H-pyrazol-3-yl)carbonyl)amino)-3-pyridinecarboxylic acid

Chemical Property of 6-(((1-((5-chloro-2-phenyl-benzofuran-7-yl)methyl)-5-methyl-1H-pyrazol-3-yl)carbonyl)amino)-3-pyridinecarboxylic acid

Chemical Property:

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Technology Process of 6-(((1-((5-chloro-2-phenyl-benzofuran-7-yl)methyl)-5-methyl-1H-pyrazol-3-yl)carbonyl)amino)-3-pyridinecarboxylic acid

There total 1 articles about 6-(((1-((5-chloro-2-phenyl-benzofuran-7-yl)methyl)-5-methyl-1H-pyrazol-3-yl)carbonyl)amino)-3-pyridinecarboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 6-(((1-((5-chloro-2-phenyl-benzofuran-7-yl)methyl)-5-methyl-1H-pyrazol-3-yl)carbonyl)amino)-3-pyridinecarboxylate (1048994-07-5) → 6-(((1-((5-chloro-2-phenyl-benzofuran-7-yl)methyl)-5-methyl-1H-pyrazol-3-yl)carbonyl)amino)-3-pyridinecarboxylic acid (1048994-08-6)

Guidance literature:

methyl 6-(((1-((5-chloro-2-phenyl-benzofuran-7-yl)methyl)-5-methyl-1H-pyrazol-3-yl)carbonyl)amino)-3-pyridinecarboxylate; With sodium hydroxide; ethanol; water; at 90 ℃; for 0.5h;

With hydrogenchloride; water; pH=1;

Reference yield:

6-(((1-((5-chloro-2-phenyl-benzofuran-7-yl)methyl)-5-methyl-1H-pyrazol-3-yl)carbonyl)amino)-3-pyridinecarboxylic acid (1048994-08-6) + tert-butyl 4-(aminomethyl)piperidine-1-carboxylate (144222-22-0) → 1,1-dimethylethyl 4-((((6-(((1-((5-chloro-2-phenyl-benzofuran-7-yl)methyl)-5-methyl-1H-pyrazol-3-yl)carbonyl)amino)-3-pyridinyl)carbonyl)amino)methyl)-1-piperidinecarboxylate (1048994-09-7)

Guidance literature:

With N-ethylmorpholine;; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In N,N-dimethyl-formamide;

upstream raw materials:

methyl 6-(((1-((5-chloro-2-phenyl-benzofuran-7-yl)methyl)-5-methyl-1H-pyrazol-3-yl)carbonyl)amino)-3-pyridinecarboxylate

Downstream raw materials:

1,1-dimethylethyl 4-((((6-(((1-((5-chloro-2-phenyl-benzofuran-7-yl)methyl)-5-methyl-1H-pyrazol-3-yl)carbonyl)amino)-3-pyridinyl)carbonyl)amino)methyl)-1-piperidinecarboxylate

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