C₁₅H₁₅BrClNO₄

Base Information

• Chemical Name: C₁₅H₁₅BrClNO₄
• CAS No.: 902132-64-3
• Molecular Formula: C₁₅H₁₅BrClNO₄
• Molecular Weight: 388.645
• Mol file: 902132-64-3.mol

Synonyms:C₁₅H₁₅BrClNO₄

Chemical Property of C₁₅H₁₅BrClNO₄

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₁₅H₁₅BrClNO₄

There total 2 articles about C₁₅H₁₅BrClNO₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C20H31BClNO3 + 2-bromoacrolein (14925-39-4) → C15H15BrClNO4 (902132-64-3)

Guidance literature:

C₂₀H₃₁BClNO₃; 2-bromoacrolein; In dichloromethane; at -78 - 25 ℃; for 21h;

With dihydrogen peroxide; In methanol; dichloromethane; at 0 ℃; for 1h; Further stages.;

DOI:10.1039/b602020h

Reference yield:

(4S)-(+)-3-(chloroacetyl)-4-(phenylmethyl)-2-oxazolidinone (104324-16-5) → C15H15BrClNO4 (902132-64-3)

Guidance literature:

Multi-step reaction with 2 steps

1.1: i-Pr₂NEt / CH₂Cl₂ / 2 h / -78 - 25 °C

2.1: CH₂Cl₂ / 21 h / -78 - 25 °C

2.2: 28.90 g / aq. pH 7.0 buffer; H₂O₂ / CH₂Cl₂; methanol / 1 h / 0 °C

With N-ethyl-N,N-diisopropylamine; In dichloromethane; 2.1: Evans aldol reaction;

DOI:10.1039/b602020h

Reference yield: 81.0%

C15H15BrClNO4 (902132-64-3) → C15H16BrNO4 (902132-65-4)

Guidance literature:

With ammonium chloride; zinc; In methanol; at 25 ℃; for 6h;

DOI:10.1039/b602020h

upstream raw materials:

2-bromoacrolein

(4S)-(+)-3-(chloroacetyl)-4-(phenylmethyl)-2-oxazolidinone

Downstream raw materials:

C₁₅H₁₆BrNO₄

C₅₈H₉₅BrO₁₀Si₂

C₂₁H₃₀BrNO₄Si

C₂₇H₄₃BrO₅Si